Hoffmann’s disease: MR imaging of hypothyroid myopathy

Jeewon Chung; Kyung Sik Ahn; Chang Ho Kang; Suk-Joo Hong; Beak Hyun Kim

doi:10.1007/s00256-015-2226-1

Hoffmann’s disease: MR imaging of hypothyroid myopathy

Jeewon Chung, Kyung Sik Ahn, Chang Ho Kang, Suk-Joo Hong, Beak Hyun Kim

Department of Radiology

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

Hoffmann’s syndrome is a hypothyroid myopathy presenting as muscle stiffness and hypertrophy. It is a rare complication of hypothyroidism. MRI features of this syndrome have seldom been described in the literature. We present a case of Hoffmann’s syndrome in a 34-year-old man who underwent lower extremity contrast-enhanced MRI. MRI can demonstrate the hypertrophic configuration, T2 hyperintensity, and enhancement of the involved muscles in Hoffmann’s syndrome. Along with clinical, laboratory, and electromyography findings, MRI may be helpful in distinguishing between inflammatory myopathy, myonecrosis, subacute muscle denervation, and infectious myositis.

Original language	English
Pages (from-to)	1701-1704
Number of pages	4
Journal	Skeletal Radiology
Volume	44
Issue number	11
DOIs	https://doi.org/10.1007/s00256-015-2226-1
Publication status	Published - 2015 Nov 26

Keywords

Hoffmann’s syndrome
Hypothyroidism
Magnetic resonance imaging
Myopathy

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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Cite this

Chung, J., Ahn, K. S., Kang, C. H., Hong, S-J., & Kim, B. H. (2015). Hoffmann’s disease: MR imaging of hypothyroid myopathy. Skeletal Radiology, 44(11), 1701-1704. https://doi.org/10.1007/s00256-015-2226-1

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abstract = "Hoffmann{\textquoteright}s syndrome is a hypothyroid myopathy presenting as muscle stiffness and hypertrophy. It is a rare complication of hypothyroidism. MRI features of this syndrome have seldom been described in the literature. We present a case of Hoffmann{\textquoteright}s syndrome in a 34-year-old man who underwent lower extremity contrast-enhanced MRI. MRI can demonstrate the hypertrophic configuration, T2 hyperintensity, and enhancement of the involved muscles in Hoffmann{\textquoteright}s syndrome. Along with clinical, laboratory, and electromyography findings, MRI may be helpful in distinguishing between inflammatory myopathy, myonecrosis, subacute muscle denervation, and infectious myositis.",

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