Abstract
Hoffmann’s syndrome is a hypothyroid myopathy presenting as muscle stiffness and hypertrophy. It is a rare complication of hypothyroidism. MRI features of this syndrome have seldom been described in the literature. We present a case of Hoffmann’s syndrome in a 34-year-old man who underwent lower extremity contrast-enhanced MRI. MRI can demonstrate the hypertrophic configuration, T2 hyperintensity, and enhancement of the involved muscles in Hoffmann’s syndrome. Along with clinical, laboratory, and electromyography findings, MRI may be helpful in distinguishing between inflammatory myopathy, myonecrosis, subacute muscle denervation, and infectious myositis.
| Original language | English |
|---|---|
| Pages (from-to) | 1701-1704 |
| Number of pages | 4 |
| Journal | Skeletal Radiology |
| Volume | 44 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2015 Nov 26 |
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Keywords
- Hoffmann’s syndrome
- Hypothyroidism
- Magnetic resonance imaging
- Myopathy
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Hoffmann’s disease : MR imaging of hypothyroid myopathy. / Chung, Jeewon; Ahn, Kyung Sik; Kang, Chang Ho; Hong, Suk-Joo; Kim, Beak Hyun.
In: Skeletal Radiology, Vol. 44, No. 11, 26.11.2015, p. 1701-1704.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hoffmann’s disease
T2 - MR imaging of hypothyroid myopathy
AU - Chung, Jeewon
AU - Ahn, Kyung Sik
AU - Kang, Chang Ho
AU - Hong, Suk-Joo
AU - Kim, Beak Hyun
PY - 2015/11/26
Y1 - 2015/11/26
N2 - Hoffmann’s syndrome is a hypothyroid myopathy presenting as muscle stiffness and hypertrophy. It is a rare complication of hypothyroidism. MRI features of this syndrome have seldom been described in the literature. We present a case of Hoffmann’s syndrome in a 34-year-old man who underwent lower extremity contrast-enhanced MRI. MRI can demonstrate the hypertrophic configuration, T2 hyperintensity, and enhancement of the involved muscles in Hoffmann’s syndrome. Along with clinical, laboratory, and electromyography findings, MRI may be helpful in distinguishing between inflammatory myopathy, myonecrosis, subacute muscle denervation, and infectious myositis.
AB - Hoffmann’s syndrome is a hypothyroid myopathy presenting as muscle stiffness and hypertrophy. It is a rare complication of hypothyroidism. MRI features of this syndrome have seldom been described in the literature. We present a case of Hoffmann’s syndrome in a 34-year-old man who underwent lower extremity contrast-enhanced MRI. MRI can demonstrate the hypertrophic configuration, T2 hyperintensity, and enhancement of the involved muscles in Hoffmann’s syndrome. Along with clinical, laboratory, and electromyography findings, MRI may be helpful in distinguishing between inflammatory myopathy, myonecrosis, subacute muscle denervation, and infectious myositis.
KW - Hoffmann’s syndrome
KW - Hypothyroidism
KW - Magnetic resonance imaging
KW - Myopathy
UR - http://www.scopus.com/inward/record.url?scp=84942296054&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84942296054&partnerID=8YFLogxK
U2 - 10.1007/s00256-015-2226-1
DO - 10.1007/s00256-015-2226-1
M3 - Article
C2 - 26250555
AN - SCOPUS:84942296054
VL - 44
SP - 1701
EP - 1704
JO - Skeletal Radiology
JF - Skeletal Radiology
SN - 0364-2348
IS - 11
ER -