Hook-wire localization versus lipiodol localization for patients with pulmonary lesions having ground-glass opacity

LOGIS investigators

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objectives: Accurate and safe preoperative localization is useful for video-assisted thoracic surgery of small pulmonary lesions with ground-glass opacity (GGO). However, the optimal localization method is unclear. The aim of this study was to compare the usefulness and safety of the lipiodol and hook-wire localization techniques for video-assisted thoracic surgery of GGO lesions. Methods: This prospective, non-randomized comparative study was conducted between April 2014 and December 2016 at 8 qualifying university teaching hospitals. Two-hundred-fifty patients with pulmonary lesions having GGO were included. Patients were assigned in a 1:1 ratio to either the lipiodol (n = 125, 4 hospitals) or hook-wire group (n = 125, 4 hospitals) for preoperative localization procedures. Participants underwent preoperative localization via the lipiodol or hook-wire technique followed by thoracoscopic surgery. The primary endpoint was the procedure success rate. Results: The procedure success rates (hook-wire vs lipiodol group) were 94.40% versus 99.16% (P =.08). Localization-related complications occurred in 53.60% versus 48.33% of patients (P =.49). Hemorrhage rates were significantly greater in the hook-wire group than in the lipiodol group (21.6% vs 5.83%, P <.001). The lipiodol procedure time was significantly longer than that of the hook-wire technique (20.69 ± 9.34 vs 17.15 ± 7.91 minutes, P =.001). The initially positive surgical resection margin was significantly greater in the hook-wire group than in the lipiodol group (10.89% vs 2.38%, P =.02). Conclusions: There was no significant difference in success rate between the hook-wire and lipiodol methods. However, the hemorrhage rate was significantly greater in the hook-wire group, whereas the hook-wire group showed greater initially positive surgical resection margins.

Original languageEnglish
JournalJournal of Thoracic and Cardiovascular Surgery
DOIs
Publication statusAccepted/In press - 2019 Jan 1

Fingerprint

Ethiodized Oil
Glass
Lung
Video-Assisted Thoracic Surgery
Hemorrhage
Preoperative Care
Thoracoscopy
Teaching Hospitals
Safety
Margins of Excision

Keywords

  • ground-glass opacity
  • hook-wire
  • lipiodol
  • localization
  • video-assisted thoracic surgery

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

@article{4a1c9d2a27fe45c2b2c9e8e1f4acdd0c,
title = "Hook-wire localization versus lipiodol localization for patients with pulmonary lesions having ground-glass opacity",
abstract = "Objectives: Accurate and safe preoperative localization is useful for video-assisted thoracic surgery of small pulmonary lesions with ground-glass opacity (GGO). However, the optimal localization method is unclear. The aim of this study was to compare the usefulness and safety of the lipiodol and hook-wire localization techniques for video-assisted thoracic surgery of GGO lesions. Methods: This prospective, non-randomized comparative study was conducted between April 2014 and December 2016 at 8 qualifying university teaching hospitals. Two-hundred-fifty patients with pulmonary lesions having GGO were included. Patients were assigned in a 1:1 ratio to either the lipiodol (n = 125, 4 hospitals) or hook-wire group (n = 125, 4 hospitals) for preoperative localization procedures. Participants underwent preoperative localization via the lipiodol or hook-wire technique followed by thoracoscopic surgery. The primary endpoint was the procedure success rate. Results: The procedure success rates (hook-wire vs lipiodol group) were 94.40{\%} versus 99.16{\%} (P =.08). Localization-related complications occurred in 53.60{\%} versus 48.33{\%} of patients (P =.49). Hemorrhage rates were significantly greater in the hook-wire group than in the lipiodol group (21.6{\%} vs 5.83{\%}, P <.001). The lipiodol procedure time was significantly longer than that of the hook-wire technique (20.69 ± 9.34 vs 17.15 ± 7.91 minutes, P =.001). The initially positive surgical resection margin was significantly greater in the hook-wire group than in the lipiodol group (10.89{\%} vs 2.38{\%}, P =.02). Conclusions: There was no significant difference in success rate between the hook-wire and lipiodol methods. However, the hemorrhage rate was significantly greater in the hook-wire group, whereas the hook-wire group showed greater initially positive surgical resection margins.",
keywords = "ground-glass opacity, hook-wire, lipiodol, localization, video-assisted thoracic surgery",
author = "{LOGIS investigators} and Park, {Chul Hwan} and Lee, {Sang Min} and Lee, {Ji Won} and Hwang, {Sung Ho} and Woocheol Kwon and Kyunghwa Han and Jin Hur and Seo, {Jae Seung} and Lee, {Kye Ho} and Im, {Dong Jin} and Kim, {Tae Hoon} and Choi, {Byoung Wook}",
year = "2019",
month = "1",
day = "1",
doi = "10.1016/j.jtcvs.2019.08.100",
language = "English",
journal = "Journal of Thoracic and Cardiovascular Surgery",
issn = "0022-5223",
publisher = "Mosby Inc.",

}

TY - JOUR

T1 - Hook-wire localization versus lipiodol localization for patients with pulmonary lesions having ground-glass opacity

AU - LOGIS investigators

AU - Park, Chul Hwan

AU - Lee, Sang Min

AU - Lee, Ji Won

AU - Hwang, Sung Ho

AU - Kwon, Woocheol

AU - Han, Kyunghwa

AU - Hur, Jin

AU - Seo, Jae Seung

AU - Lee, Kye Ho

AU - Im, Dong Jin

AU - Kim, Tae Hoon

AU - Choi, Byoung Wook

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objectives: Accurate and safe preoperative localization is useful for video-assisted thoracic surgery of small pulmonary lesions with ground-glass opacity (GGO). However, the optimal localization method is unclear. The aim of this study was to compare the usefulness and safety of the lipiodol and hook-wire localization techniques for video-assisted thoracic surgery of GGO lesions. Methods: This prospective, non-randomized comparative study was conducted between April 2014 and December 2016 at 8 qualifying university teaching hospitals. Two-hundred-fifty patients with pulmonary lesions having GGO were included. Patients were assigned in a 1:1 ratio to either the lipiodol (n = 125, 4 hospitals) or hook-wire group (n = 125, 4 hospitals) for preoperative localization procedures. Participants underwent preoperative localization via the lipiodol or hook-wire technique followed by thoracoscopic surgery. The primary endpoint was the procedure success rate. Results: The procedure success rates (hook-wire vs lipiodol group) were 94.40% versus 99.16% (P =.08). Localization-related complications occurred in 53.60% versus 48.33% of patients (P =.49). Hemorrhage rates were significantly greater in the hook-wire group than in the lipiodol group (21.6% vs 5.83%, P <.001). The lipiodol procedure time was significantly longer than that of the hook-wire technique (20.69 ± 9.34 vs 17.15 ± 7.91 minutes, P =.001). The initially positive surgical resection margin was significantly greater in the hook-wire group than in the lipiodol group (10.89% vs 2.38%, P =.02). Conclusions: There was no significant difference in success rate between the hook-wire and lipiodol methods. However, the hemorrhage rate was significantly greater in the hook-wire group, whereas the hook-wire group showed greater initially positive surgical resection margins.

AB - Objectives: Accurate and safe preoperative localization is useful for video-assisted thoracic surgery of small pulmonary lesions with ground-glass opacity (GGO). However, the optimal localization method is unclear. The aim of this study was to compare the usefulness and safety of the lipiodol and hook-wire localization techniques for video-assisted thoracic surgery of GGO lesions. Methods: This prospective, non-randomized comparative study was conducted between April 2014 and December 2016 at 8 qualifying university teaching hospitals. Two-hundred-fifty patients with pulmonary lesions having GGO were included. Patients were assigned in a 1:1 ratio to either the lipiodol (n = 125, 4 hospitals) or hook-wire group (n = 125, 4 hospitals) for preoperative localization procedures. Participants underwent preoperative localization via the lipiodol or hook-wire technique followed by thoracoscopic surgery. The primary endpoint was the procedure success rate. Results: The procedure success rates (hook-wire vs lipiodol group) were 94.40% versus 99.16% (P =.08). Localization-related complications occurred in 53.60% versus 48.33% of patients (P =.49). Hemorrhage rates were significantly greater in the hook-wire group than in the lipiodol group (21.6% vs 5.83%, P <.001). The lipiodol procedure time was significantly longer than that of the hook-wire technique (20.69 ± 9.34 vs 17.15 ± 7.91 minutes, P =.001). The initially positive surgical resection margin was significantly greater in the hook-wire group than in the lipiodol group (10.89% vs 2.38%, P =.02). Conclusions: There was no significant difference in success rate between the hook-wire and lipiodol methods. However, the hemorrhage rate was significantly greater in the hook-wire group, whereas the hook-wire group showed greater initially positive surgical resection margins.

KW - ground-glass opacity

KW - hook-wire

KW - lipiodol

KW - localization

KW - video-assisted thoracic surgery

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DO - 10.1016/j.jtcvs.2019.08.100

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JO - Journal of Thoracic and Cardiovascular Surgery

JF - Journal of Thoracic and Cardiovascular Surgery

SN - 0022-5223

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