Host switch during evolution of a genetically distinct hantavirus in the American shrew mole (Neurotrichus gibbsii)

Hae Ji Kang, Shannon N. Bennett, Laurie Dizney, Laarni Sumibcay, Satoru Arai, Luis A. Ruedas, Jin Won Song, Richard Yanagihara

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61 Citations (Scopus)

Abstract

A genetically distinct hantavirus, designated Oxbow virus (OXBV), was detected in tissues of an American shrew mole (Neurotrichus gibbsii), captured in Gresham, Oregon, in September 2003. Pairwise analysis of full-length S- and M- and partial L-segment nucleotide and amino acid sequences of OXBV indicated low sequence similarity with rodent-borne hantaviruses. Phylogenetic analyses using maximum-likelihood and Bayesian methods, and host-parasite evolutionary comparisons, showed that OXBV and Asama virus, a hantavirus recently identified from the Japanese shrew mole (Urotrichus talpoides), were related to soricine shrew-borne hantaviruses from North America and Eurasia, respectively, suggesting parallel evolution associated with cross-species transmission.

Original languageEnglish
Pages (from-to)8-14
Number of pages7
JournalVirology
Volume388
Issue number1
DOIs
Publication statusPublished - 2009 May 25
Externally publishedYes

Keywords

  • Hantavirus
  • Host switching
  • Phylogeny
  • Soricid
  • Talpid

ASJC Scopus subject areas

  • Virology

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    Ji Kang, H., Bennett, S. N., Dizney, L., Sumibcay, L., Arai, S., Ruedas, L. A., Song, J. W., & Yanagihara, R. (2009). Host switch during evolution of a genetically distinct hantavirus in the American shrew mole (Neurotrichus gibbsii). Virology, 388(1), 8-14. https://doi.org/10.1016/j.virol.2009.03.019