Human herpesvirus 8-negative and Epstein-Barr virus-positive effusion-based lymphoma in a patient with human immunodeficiency virus

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Abstract

A 39-year-old man infected with human immunodeficiency virus (HIV) was admitted to our hospital because of sudden onset of chest pain. Chest radiography revealed pneumothorax of the right lung. Computed tomographic scans disclosed a 5.8-cm-sized emphysematous bulla in the right middle lobe of the lung. Histologically, the wedge-resected lung showed medium to large atypical cells within the bullous cavity of the Pneumocystis jirovecii pneumonia, without solid mass formation. These atypical cells were confirmed to be large B-cell lymphoma, Epstein-Barr virus-positive and human herpesvirus 8-negative. Therefore, this case was not diagnosed as primary effusion lymphoma, but effusion-based lymphoma arising in an emphysematous cavity of an HIV-infected patient. This type of effusion-based lymphoma has never been reported, and, although rare, it should be noted in order to clinically diagnose this lymphoma.

Original languageEnglish
Pages (from-to)409-412
Number of pages4
JournalJournal of Pathology and Translational Medicine
Volume49
Issue number5
DOIs
Publication statusPublished - 2015

Fingerprint

Human Herpesvirus 8
Human Herpesvirus 4
Lymphoma
HIV
Lung
Primary Effusion Lymphoma
Pneumocystis carinii
Pneumocystis Pneumonia
B-Cell Lymphoma
Pneumothorax
Blister
Chest Pain
Radiography
Thorax

Keywords

  • Effusion-based lymphoma
  • Epstein-Barr virus
  • HIV
  • Human herpesvirus 8

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

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title = "Human herpesvirus 8-negative and Epstein-Barr virus-positive effusion-based lymphoma in a patient with human immunodeficiency virus",
abstract = "A 39-year-old man infected with human immunodeficiency virus (HIV) was admitted to our hospital because of sudden onset of chest pain. Chest radiography revealed pneumothorax of the right lung. Computed tomographic scans disclosed a 5.8-cm-sized emphysematous bulla in the right middle lobe of the lung. Histologically, the wedge-resected lung showed medium to large atypical cells within the bullous cavity of the Pneumocystis jirovecii pneumonia, without solid mass formation. These atypical cells were confirmed to be large B-cell lymphoma, Epstein-Barr virus-positive and human herpesvirus 8-negative. Therefore, this case was not diagnosed as primary effusion lymphoma, but effusion-based lymphoma arising in an emphysematous cavity of an HIV-infected patient. This type of effusion-based lymphoma has never been reported, and, although rare, it should be noted in order to clinically diagnose this lymphoma.",
keywords = "Effusion-based lymphoma, Epstein-Barr virus, HIV, Human herpesvirus 8",
author = "Jung-Woo Choi and Younghye Kim and Ju-Han Lee and Kim, {Young Sik}",
year = "2015",
doi = "10.4132/jptm.2015.06.03",
language = "English",
volume = "49",
pages = "409--412",
journal = "Journal of Pathology and Translational Medicine",
issn = "2383-7837",
publisher = "Korean Society of Pathologists",
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TY - JOUR

T1 - Human herpesvirus 8-negative and Epstein-Barr virus-positive effusion-based lymphoma in a patient with human immunodeficiency virus

AU - Choi, Jung-Woo

AU - Kim, Younghye

AU - Lee, Ju-Han

AU - Kim, Young Sik

PY - 2015

Y1 - 2015

N2 - A 39-year-old man infected with human immunodeficiency virus (HIV) was admitted to our hospital because of sudden onset of chest pain. Chest radiography revealed pneumothorax of the right lung. Computed tomographic scans disclosed a 5.8-cm-sized emphysematous bulla in the right middle lobe of the lung. Histologically, the wedge-resected lung showed medium to large atypical cells within the bullous cavity of the Pneumocystis jirovecii pneumonia, without solid mass formation. These atypical cells were confirmed to be large B-cell lymphoma, Epstein-Barr virus-positive and human herpesvirus 8-negative. Therefore, this case was not diagnosed as primary effusion lymphoma, but effusion-based lymphoma arising in an emphysematous cavity of an HIV-infected patient. This type of effusion-based lymphoma has never been reported, and, although rare, it should be noted in order to clinically diagnose this lymphoma.

AB - A 39-year-old man infected with human immunodeficiency virus (HIV) was admitted to our hospital because of sudden onset of chest pain. Chest radiography revealed pneumothorax of the right lung. Computed tomographic scans disclosed a 5.8-cm-sized emphysematous bulla in the right middle lobe of the lung. Histologically, the wedge-resected lung showed medium to large atypical cells within the bullous cavity of the Pneumocystis jirovecii pneumonia, without solid mass formation. These atypical cells were confirmed to be large B-cell lymphoma, Epstein-Barr virus-positive and human herpesvirus 8-negative. Therefore, this case was not diagnosed as primary effusion lymphoma, but effusion-based lymphoma arising in an emphysematous cavity of an HIV-infected patient. This type of effusion-based lymphoma has never been reported, and, although rare, it should be noted in order to clinically diagnose this lymphoma.

KW - Effusion-based lymphoma

KW - Epstein-Barr virus

KW - HIV

KW - Human herpesvirus 8

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