Hydrodynamic microfabrication via "on the fly" photopolymerization of microscale fibers and tubes

Wonje Jeong, Jeongyun Kim, Sunjeong Kim, Sang Hoon Lee, Glennys Mensing, David J. Beebe

Research output: Contribution to journalArticle

181 Citations (Scopus)


A microfluidic apparatus capable of creating continuous microscale cylindrical polymeric structures has been developed. This system is able to produce microstructures (e.g. fibers, tubes) by employing 3D multiple stream laminar flow and "on the fly" in-situ photopolymerization. The details of the fabrication process and the characterization of the produced microfibers are described. The apparatus is constructed by merging pulled glass pipettes with PDMS molding technology and used to manufacture the fibers and tubes. By controlling the sample and sheath volume flow rates, the dimensions of the microstructures produced can be altered without re-tooling. The fiber properties including elasticity, stimuli responsiveness, and biosensing are characterized. Responsive woven fabric and biosensing fibers are demonstrated. The fabrication process is simple, cost effective and flexible in materials, geometries, and scales.

Original languageEnglish
Pages (from-to)576-580
Number of pages5
JournalLab on a Chip - Miniaturisation for Chemistry and Biology
Issue number6
Publication statusPublished - 2004 Dec 1
Externally publishedYes


ASJC Scopus subject areas

  • Clinical Biochemistry

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