Identification of oxidative stress and estrogenic activity induced by polarity fractions of effluent organic matter

Jisu Yoo, Jin Hur, Jinho Jung

Research output: Contribution to journalArticle

Abstract

This study evaluated oxidative stress and estrogenic activity induced by hydrophobic (HP), transphilic (TP), and hydrophilic (HL)fractions of effluent organic matter (EfOM)from municipal and industrial wastewater treatment plants. Fluorescence regional integration (FRI)analysis indicated that EfOM showed higher FRI distribution in regions II (aromatic protein-like)and IV (soluble microbial products, SMPs)than Suwannee River natural organic matter (SRNOM), which was primarily in regions III (fulvic acid-like)and V (humic acid-like). The HP and HL fractions of industrial EfOMs significantly increased catalase (CAT)and glutathione S-transferase (GST)activity and lipid peroxidation compared with those of the control (p < 0.05). Estrogenic activity was the highest in industrial EfOM followed by municipal EfOM, and both were significantly higher than that of SRNOM and the control (p < 0.05). FRI distribution in region II was significantly related to CAT, GST, and estrogenic activity (r = 0.7142, 0.7786, and 0.8107, respectively)for the HL fraction of EfOM. For the HP fraction of EfOM, regions II and IV were significantly related to estrogenic activity (r = 0.7221 and 0.6707, respectively). These findings suggest that aromatic protein-like substances and SMPs in EfOM were responsible for the observed oxidative stress and estrogenic activity.

Original languageEnglish
Pages (from-to)264-272
Number of pages9
JournalJournal of Hazardous Materials
Volume375
DOIs
Publication statusPublished - 2019 Aug 5

Fingerprint

Oxidative stress
Biological materials
Effluents
Oxidative Stress
Fluorescence
effluent
Glutathione Transferase
Rivers
organic matter
Catalase
Humic Substances
Waste Water
Lipid Peroxidation
Proteins
fluorescence
oxidative stress
protein
fulvic acid
river
Wastewater treatment

Keywords

  • Effluent
  • Estrogenic activity
  • Organic matter
  • Oxidative stress
  • Polarity

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

Identification of oxidative stress and estrogenic activity induced by polarity fractions of effluent organic matter. / Yoo, Jisu; Hur, Jin; Jung, Jinho.

In: Journal of Hazardous Materials, Vol. 375, 05.08.2019, p. 264-272.

Research output: Contribution to journalArticle

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