Identification of tissue-specific expression of CXCL14 in black rockfish (Sebastes schlegelii)

Hyocheol Bae, Changwon Yang, Whasun Lim, Gwonhwa Song

Research output: Contribution to journalArticlepeer-review

Abstract

CXCL14 is a chemokine which is orthologous in mammals and fish. CXCL14 has a functional role in different organs, with immunomodulatory functions in mammals, but its expression and function in fish is not well known. Moreover, it shows no effects related to immunity in the central nervous system or the reproductive tract in diverse species. Black rockfish (Sebastes schlegelii) is an economically important fish in Asian countries, whose CXCL14 expression pattern is yet to be understood. In this study, the homology of the CXCL14 amino acid sequence in S. schlegelii was compared with that in other species, including fish. Moreover, in situ hybridization analysis revealed that it was highly expressed in the brain and ovary of S. schlegelii. Taken together, we identified for the first time, the cell-specific expression of CXCL14 in S. schlegelii.

Original languageEnglish
Pages (from-to)135-142
Number of pages8
JournalFish and Shellfish Immunology
Volume112
DOIs
Publication statusPublished - 2021 May
Externally publishedYes

Keywords

  • Black rockfish
  • Brain
  • CXCL14
  • Messenger RNA
  • Ovary

ASJC Scopus subject areas

  • Environmental Chemistry
  • Aquatic Science

Fingerprint Dive into the research topics of 'Identification of tissue-specific expression of CXCL14 in black rockfish (Sebastes schlegelii)'. Together they form a unique fingerprint.

Cite this