Ileocolonoscopic and histologic studies of Korean patients with ankylosing spondylitis

Y. H. Lee, J. D. Ji, J. S. Kim, Y. T. Bak, C. H. Lee, C. H. Kim, Y. S. Chae, G. G. Song

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15 Citations (Scopus)

Abstract

We investigated the frequency of gut inflammation and the role of gut lesion in the pathogenesis of the ankylosing spondylitis (AS) in Korean patients. Ileocolonoscopy and biopsy of the colon and terminal ileum were performed on 24 Korean patients with AS. Endoscopic lesions were observed in 7 patients (29.2%). The lesions were found more often in the terminal ileum (6/7) than in the colon (1/7). Histologic signs of gut inflammation were detected in 14 patients (58.3%), acute lesions in 2 patients (8.3%) and chronic lesions in 12 patients (50%). Gut inflammation were as frequently found in Korean patients with AS as in Western patients. These findings suggest that gut inflammation may play a role in the pathogenesis of AS in Korean patients as it does in Western patients.

Original languageEnglish
Pages (from-to)473-476
Number of pages4
JournalScandinavian Journal of Rheumatology
Volume26
Issue number6
DOIs
Publication statusPublished - 1997

Keywords

  • Ankylosing spondylitis
  • Ileocolonoscopic and Histologic studies

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology

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    Lee, Y. H., Ji, J. D., Kim, J. S., Bak, Y. T., Lee, C. H., Kim, C. H., Chae, Y. S., & Song, G. G. (1997). Ileocolonoscopic and histologic studies of Korean patients with ankylosing spondylitis. Scandinavian Journal of Rheumatology, 26(6), 473-476. https://doi.org/10.3109/03009749709065722