IM-MS for Supramolecular Systems

Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase

Tae Su Choi, Jongcheol Seo, Hugh I. Kim

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Ion mobility mass spectrometry (IM-MS) has been broadly utilized in the structural characterization of noncovalent, supramolecular complexes. In this chapter, we discuss three types of supramolecular complexes, and their structural dynamics observed in IM-MS studies. Firstly, host–guest chemistry of cucurbituril, crown ether, and cyclodextrin is discussed. Secondly, self-assembly mechanisms of amino acids and peptides are introduced. Finally, structural studies of protein–protein complexes are presented. We mainly focus on insights into the physicochemical properties of supramolecular complexes (e.g. molecular interactions, role of water molecules in complexation and structural features).

Original languageEnglish
Title of host publicationComprehensive Analytical Chemistry
PublisherElsevier B.V.
Pages197-236
Number of pages40
DOIs
Publication statusPublished - 2019 Jan 1

Publication series

NameComprehensive Analytical Chemistry
Volume83
ISSN (Print)0166-526X

Fingerprint

Mass spectrometry
Gases
Ions
Crown Ethers
Molecular interactions
Structural dynamics
Cyclodextrins
Complexation
Self assembly
Amino Acids
Peptides
Molecules
Water
cucurbituril

Keywords

  • Host–guest chemistry
  • Ion mobility mass spectrometry
  • Protein–protein complex
  • Self-assembly

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

Choi, T. S., Seo, J., & Kim, H. I. (2019). IM-MS for Supramolecular Systems: Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase. In Comprehensive Analytical Chemistry (pp. 197-236). (Comprehensive Analytical Chemistry; Vol. 83). Elsevier B.V.. https://doi.org/10.1016/bs.coac.2018.09.002

IM-MS for Supramolecular Systems : Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase. / Choi, Tae Su; Seo, Jongcheol; Kim, Hugh I.

Comprehensive Analytical Chemistry. Elsevier B.V., 2019. p. 197-236 (Comprehensive Analytical Chemistry; Vol. 83).

Research output: Chapter in Book/Report/Conference proceedingChapter

Choi, TS, Seo, J & Kim, HI 2019, IM-MS for Supramolecular Systems: Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase. in Comprehensive Analytical Chemistry. Comprehensive Analytical Chemistry, vol. 83, Elsevier B.V., pp. 197-236. https://doi.org/10.1016/bs.coac.2018.09.002
Choi TS, Seo J, Kim HI. IM-MS for Supramolecular Systems: Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase. In Comprehensive Analytical Chemistry. Elsevier B.V. 2019. p. 197-236. (Comprehensive Analytical Chemistry). https://doi.org/10.1016/bs.coac.2018.09.002
Choi, Tae Su ; Seo, Jongcheol ; Kim, Hugh I. / IM-MS for Supramolecular Systems : Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase. Comprehensive Analytical Chemistry. Elsevier B.V., 2019. pp. 197-236 (Comprehensive Analytical Chemistry).
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