Abstract
Ion mobility mass spectrometry (IM-MS) has been broadly utilized in the structural characterization of noncovalent, supramolecular complexes. In this chapter, we discuss three types of supramolecular complexes, and their structural dynamics observed in IM-MS studies. Firstly, host–guest chemistry of cucurbituril, crown ether, and cyclodextrin is discussed. Secondly, self-assembly mechanisms of amino acids and peptides are introduced. Finally, structural studies of protein–protein complexes are presented. We mainly focus on insights into the physicochemical properties of supramolecular complexes (e.g. molecular interactions, role of water molecules in complexation and structural features).
| Original language | English |
|---|---|
| Title of host publication | Comprehensive Analytical Chemistry |
| Publisher | Elsevier B.V. |
| Pages | 197-236 |
| Number of pages | 40 |
| DOIs | |
| Publication status | Published - 2019 Jan 1 |
Publication series
| Name | Comprehensive Analytical Chemistry |
|---|---|
| Volume | 83 |
| ISSN (Print) | 0166-526X |
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Keywords
- Host–guest chemistry
- Ion mobility mass spectrometry
- Protein–protein complex
- Self-assembly
ASJC Scopus subject areas
- Analytical Chemistry
- Spectroscopy
Cite this
IM-MS for Supramolecular Systems : Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase. / Choi, Tae Su; Seo, Jongcheol; Kim, Hugh I.
Comprehensive Analytical Chemistry. Elsevier B.V., 2019. p. 197-236 (Comprehensive Analytical Chemistry; Vol. 83).Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - IM-MS for Supramolecular Systems
T2 - Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase
AU - Choi, Tae Su
AU - Seo, Jongcheol
AU - Kim, Hugh I.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Ion mobility mass spectrometry (IM-MS) has been broadly utilized in the structural characterization of noncovalent, supramolecular complexes. In this chapter, we discuss three types of supramolecular complexes, and their structural dynamics observed in IM-MS studies. Firstly, host–guest chemistry of cucurbituril, crown ether, and cyclodextrin is discussed. Secondly, self-assembly mechanisms of amino acids and peptides are introduced. Finally, structural studies of protein–protein complexes are presented. We mainly focus on insights into the physicochemical properties of supramolecular complexes (e.g. molecular interactions, role of water molecules in complexation and structural features).
AB - Ion mobility mass spectrometry (IM-MS) has been broadly utilized in the structural characterization of noncovalent, supramolecular complexes. In this chapter, we discuss three types of supramolecular complexes, and their structural dynamics observed in IM-MS studies. Firstly, host–guest chemistry of cucurbituril, crown ether, and cyclodextrin is discussed. Secondly, self-assembly mechanisms of amino acids and peptides are introduced. Finally, structural studies of protein–protein complexes are presented. We mainly focus on insights into the physicochemical properties of supramolecular complexes (e.g. molecular interactions, role of water molecules in complexation and structural features).
KW - Host–guest chemistry
KW - Ion mobility mass spectrometry
KW - Protein–protein complex
KW - Self-assembly
UR - http://www.scopus.com/inward/record.url?scp=85056251139&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85056251139&partnerID=8YFLogxK
U2 - 10.1016/bs.coac.2018.09.002
DO - 10.1016/bs.coac.2018.09.002
M3 - Chapter
T3 - Comprehensive Analytical Chemistry
SP - 197
EP - 236
BT - Comprehensive Analytical Chemistry
PB - Elsevier B.V.
ER -