TY - CHAP
T1 - IM-MS for Supramolecular Systems
T2 - Structures and Dynamics of Noncovalent Complexes From Solution to Gas Phase
AU - Choi, Tae Su
AU - Seo, Jongcheol
AU - Kim, Hugh I.
N1 - Publisher Copyright:
© 2019 Elsevier B.V.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Ion mobility mass spectrometry (IM-MS) has been broadly utilized in the structural characterization of noncovalent, supramolecular complexes. In this chapter, we discuss three types of supramolecular complexes, and their structural dynamics observed in IM-MS studies. Firstly, host–guest chemistry of cucurbituril, crown ether, and cyclodextrin is discussed. Secondly, self-assembly mechanisms of amino acids and peptides are introduced. Finally, structural studies of protein–protein complexes are presented. We mainly focus on insights into the physicochemical properties of supramolecular complexes (e.g. molecular interactions, role of water molecules in complexation and structural features).
AB - Ion mobility mass spectrometry (IM-MS) has been broadly utilized in the structural characterization of noncovalent, supramolecular complexes. In this chapter, we discuss three types of supramolecular complexes, and their structural dynamics observed in IM-MS studies. Firstly, host–guest chemistry of cucurbituril, crown ether, and cyclodextrin is discussed. Secondly, self-assembly mechanisms of amino acids and peptides are introduced. Finally, structural studies of protein–protein complexes are presented. We mainly focus on insights into the physicochemical properties of supramolecular complexes (e.g. molecular interactions, role of water molecules in complexation and structural features).
KW - Host–guest chemistry
KW - Ion mobility mass spectrometry
KW - Protein–protein complex
KW - Self-assembly
UR - http://www.scopus.com/inward/record.url?scp=85056251139&partnerID=8YFLogxK
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U2 - 10.1016/bs.coac.2018.09.002
DO - 10.1016/bs.coac.2018.09.002
M3 - Chapter
AN - SCOPUS:85056251139
T3 - Comprehensive Analytical Chemistry
SP - 197
EP - 236
BT - Comprehensive Analytical Chemistry
PB - Elsevier B.V.
ER -