Imaging voltage-dependent cell motions with heterodyne Mach-Zehnder phase microscopy

Christopher Fang-Yen, Seungeun Oh, Yongkeun Park, Wonshik Choi, Sen Song, H. Sebastian Seung, Ramachandra R. Dasari, Michael S. Feld

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We describe a heterodyne Mach-Zehnder interferometric microscope capable of quantitative phase imaging of biological samples with subnanometer sensitivity and frame rates up to 10 kHz. We use the microscope to image cultured neurons and measure nanometer-scale voltage-dependent motions in cells expressing the membrane motor protein prestin.

Original languageEnglish
Pages (from-to)1572-1574
Number of pages3
JournalOptics Letters
Volume32
Issue number11
DOIs
Publication statusPublished - 2007 Jun 1
Externally publishedYes

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Microscopy
Membrane Proteins
microscopes
Cell Membrane
microscopy
Neurons
electric potential
cells
neurons
membranes
proteins
sensitivity

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Fang-Yen, C., Oh, S., Park, Y., Choi, W., Song, S., Sebastian Seung, H., ... Feld, M. S. (2007). Imaging voltage-dependent cell motions with heterodyne Mach-Zehnder phase microscopy. Optics Letters, 32(11), 1572-1574. https://doi.org/10.1364/OL.32.001572

Imaging voltage-dependent cell motions with heterodyne Mach-Zehnder phase microscopy. / Fang-Yen, Christopher; Oh, Seungeun; Park, Yongkeun; Choi, Wonshik; Song, Sen; Sebastian Seung, H.; Dasari, Ramachandra R.; Feld, Michael S.

In: Optics Letters, Vol. 32, No. 11, 01.06.2007, p. 1572-1574.

Research output: Contribution to journalArticle

Fang-Yen, C, Oh, S, Park, Y, Choi, W, Song, S, Sebastian Seung, H, Dasari, RR & Feld, MS 2007, 'Imaging voltage-dependent cell motions with heterodyne Mach-Zehnder phase microscopy', Optics Letters, vol. 32, no. 11, pp. 1572-1574. https://doi.org/10.1364/OL.32.001572
Fang-Yen, Christopher ; Oh, Seungeun ; Park, Yongkeun ; Choi, Wonshik ; Song, Sen ; Sebastian Seung, H. ; Dasari, Ramachandra R. ; Feld, Michael S. / Imaging voltage-dependent cell motions with heterodyne Mach-Zehnder phase microscopy. In: Optics Letters. 2007 ; Vol. 32, No. 11. pp. 1572-1574.
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