Immobilization-free screening of aptamers assisted by graphene oxide

Jee Woong Park, Rameshwar Tatavarty, Dae Woo Kim, Hee Tae Jung, Man Bock Gu

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

Original languageEnglish
Pages (from-to)2071-2073
Number of pages3
JournalChemical Communications
Volume48
Issue number15
DOIs
Publication statusPublished - 2012 Feb 18

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Immobilization
Oxides
Graphene
Screening
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Proteins

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Immobilization-free screening of aptamers assisted by graphene oxide. / Park, Jee Woong; Tatavarty, Rameshwar; Kim, Dae Woo; Jung, Hee Tae; Gu, Man Bock.

In: Chemical Communications, Vol. 48, No. 15, 18.02.2012, p. 2071-2073.

Research output: Contribution to journalArticle

Park, Jee Woong ; Tatavarty, Rameshwar ; Kim, Dae Woo ; Jung, Hee Tae ; Gu, Man Bock. / Immobilization-free screening of aptamers assisted by graphene oxide. In: Chemical Communications. 2012 ; Vol. 48, No. 15. pp. 2071-2073.
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