Immobilization of fibronectin onto a large area nanoimprinted polystyrene patterns.

Wonbae Lee, You Jin Ko, Kyu Back Lee

Research output: Contribution to journalArticle

Abstract

A well known fibrous protein, fibronectin was successfully immobilized onto well-fabricated nanopatterns of polystyrene (PS) substrates. The nanopatterns with finely-defined physical dimensions were obtained by nanoimprinting lithography (NIL) using anodized aluminum oxide (AAO) molds of which the pore sizes were controlled in nanometer scale; 45 nm, 250 nm and 410 nm for the widths and 110 nm and 500 nm for the pitches. Discrete changes of the surface images before and after the protein-adsorption on the patterns were demonstrated by scanning electron microscope (SEM), and the effect of the patterned features on the immobilization has been investigated and discussed.

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ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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