Immobilization of fibronectin onto a large area nanoimprinted polystyrene patterns

Wonbae Lee, You Jin Ko, Kyu Back Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A well known fibrous protein, fibronectin was successfully immobilized onto well-fabricated nano-patterns of polystyrene (PS) substrates. The nano-patterns with finely-defined physical dimensions were obtained by nano-imprinting lithography (NIL) using anodized aluminum oxide (AAO) molds of which the pore sizes were controlled in nanometer scale; 45 nm, 250 nm and 410 nm for the widths and 110 nm and 500 nm for the pitches. Discrete changes of the surface images before and after the protein-adsorption on the patterns were demonstrated by scanning electron microscope (SEM), and the effect of the patterned features on the immobilization has been investigated and discussed.

Original languageEnglish
Title of host publication29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Pages5857-5859
Number of pages3
DOIs
Publication statusPublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: 2007 Aug 232007 Aug 26

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period07/8/2307/8/26

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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