Abstract
The polydiacetylene vesicles-based sensors have been of interest due to their unique chromatic properties, such as blue-to-red color transition. The liposome-like vesicles were immobilized on solid substrates using various polydiacetylene derivatives synthesized with different functional groups, such as, amine, carboxylic acid, and biotin, etc. Through their fluorogenic properties, the label-free biosensor was constructed with PDA immobilized on the solid substrate. Here, we showed some results of our recent studies to construct label-free sensors for detecting protein and bacterial cells using the stress-induced fluorescence emission of PDA vesicles. From the results, we anticipate that the system of micro-patterned PDA-based biosensor can be used to fabricate a label-free diagnostic sensor.
| Original language | English |
|---|---|
| Title of host publication | 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010 |
| Pages | 865-868 |
| Number of pages | 4 |
| DOIs | |
| Publication status | Published - 2010 Nov 29 |
| Event | 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010 - Xiamen, China Duration: 2010 Jan 20 → 2010 Jan 23 |
Other
| Other | 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010 |
|---|---|
| Country | China |
| City | Xiamen |
| Period | 10/1/20 → 10/1/23 |
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Keywords
- Dimyristoyl phosphatidylcholine (DMPC)
- Label-free biosensor
- Microarray
- Polydiacetylene
ASJC Scopus subject areas
- Control and Systems Engineering
- Electrical and Electronic Engineering
Cite this
Immobilized polydiacetylene vesicle for label-free biosensor. / Kim, Kyung Woo; Park, Moo Kyung; Choi, Hyun; Ahn, Dong June; Oh, Min-Kyu.
2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010. 2010. p. 865-868 5592171.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Immobilized polydiacetylene vesicle for label-free biosensor
AU - Kim, Kyung Woo
AU - Park, Moo Kyung
AU - Choi, Hyun
AU - Ahn, Dong June
AU - Oh, Min-Kyu
PY - 2010/11/29
Y1 - 2010/11/29
N2 - The polydiacetylene vesicles-based sensors have been of interest due to their unique chromatic properties, such as blue-to-red color transition. The liposome-like vesicles were immobilized on solid substrates using various polydiacetylene derivatives synthesized with different functional groups, such as, amine, carboxylic acid, and biotin, etc. Through their fluorogenic properties, the label-free biosensor was constructed with PDA immobilized on the solid substrate. Here, we showed some results of our recent studies to construct label-free sensors for detecting protein and bacterial cells using the stress-induced fluorescence emission of PDA vesicles. From the results, we anticipate that the system of micro-patterned PDA-based biosensor can be used to fabricate a label-free diagnostic sensor.
AB - The polydiacetylene vesicles-based sensors have been of interest due to their unique chromatic properties, such as blue-to-red color transition. The liposome-like vesicles were immobilized on solid substrates using various polydiacetylene derivatives synthesized with different functional groups, such as, amine, carboxylic acid, and biotin, etc. Through their fluorogenic properties, the label-free biosensor was constructed with PDA immobilized on the solid substrate. Here, we showed some results of our recent studies to construct label-free sensors for detecting protein and bacterial cells using the stress-induced fluorescence emission of PDA vesicles. From the results, we anticipate that the system of micro-patterned PDA-based biosensor can be used to fabricate a label-free diagnostic sensor.
KW - Dimyristoyl phosphatidylcholine (DMPC)
KW - Label-free biosensor
KW - Microarray
KW - Polydiacetylene
UR - http://www.scopus.com/inward/record.url?scp=78649287951&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649287951&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2010.5592171
DO - 10.1109/NEMS.2010.5592171
M3 - Conference contribution
AN - SCOPUS:78649287951
SN - 9781424465439
SP - 865
EP - 868
BT - 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010
ER -