TY - GEN
T1 - Immobilized polydiacetylene vesicle for label-free biosensor
AU - Kim, Kyung Woo
AU - Park, Moo Kyung
AU - Choi, Hyun
AU - Ahn, Dong June
AU - Oh, Min Kyu
PY - 2010
Y1 - 2010
N2 - The polydiacetylene vesicles-based sensors have been of interest due to their unique chromatic properties, such as blue-to-red color transition. The liposome-like vesicles were immobilized on solid substrates using various polydiacetylene derivatives synthesized with different functional groups, such as, amine, carboxylic acid, and biotin, etc. Through their fluorogenic properties, the label-free biosensor was constructed with PDA immobilized on the solid substrate. Here, we showed some results of our recent studies to construct label-free sensors for detecting protein and bacterial cells using the stress-induced fluorescence emission of PDA vesicles. From the results, we anticipate that the system of micro-patterned PDA-based biosensor can be used to fabricate a label-free diagnostic sensor.
AB - The polydiacetylene vesicles-based sensors have been of interest due to their unique chromatic properties, such as blue-to-red color transition. The liposome-like vesicles were immobilized on solid substrates using various polydiacetylene derivatives synthesized with different functional groups, such as, amine, carboxylic acid, and biotin, etc. Through their fluorogenic properties, the label-free biosensor was constructed with PDA immobilized on the solid substrate. Here, we showed some results of our recent studies to construct label-free sensors for detecting protein and bacterial cells using the stress-induced fluorescence emission of PDA vesicles. From the results, we anticipate that the system of micro-patterned PDA-based biosensor can be used to fabricate a label-free diagnostic sensor.
KW - Dimyristoyl phosphatidylcholine (DMPC)
KW - Label-free biosensor
KW - Microarray
KW - Polydiacetylene
UR - http://www.scopus.com/inward/record.url?scp=78649287951&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649287951&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2010.5592171
DO - 10.1109/NEMS.2010.5592171
M3 - Conference contribution
AN - SCOPUS:78649287951
SN - 9781424465439
T3 - 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010
SP - 865
EP - 868
BT - 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010
T2 - 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010
Y2 - 20 January 2010 through 23 January 2010
ER -