Immobilized polydiacetylene vesicle for label-free biosensor

Kyung Woo Kim, Moo Kyung Park, Hyun Choi, Dong June Ahn, Min-Kyu Oh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The polydiacetylene vesicles-based sensors have been of interest due to their unique chromatic properties, such as blue-to-red color transition. The liposome-like vesicles were immobilized on solid substrates using various polydiacetylene derivatives synthesized with different functional groups, such as, amine, carboxylic acid, and biotin, etc. Through their fluorogenic properties, the label-free biosensor was constructed with PDA immobilized on the solid substrate. Here, we showed some results of our recent studies to construct label-free sensors for detecting protein and bacterial cells using the stress-induced fluorescence emission of PDA vesicles. From the results, we anticipate that the system of micro-patterned PDA-based biosensor can be used to fabricate a label-free diagnostic sensor.

Original languageEnglish
Title of host publication2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010
Pages865-868
Number of pages4
DOIs
Publication statusPublished - 2010 Nov 29
Event5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010 - Xiamen, China
Duration: 2010 Jan 202010 Jan 23

Other

Other5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010
CountryChina
CityXiamen
Period10/1/2010/1/23

Fingerprint

Personal digital assistants
Biosensors
Labels
Sensors
Liposomes
Substrates
Carboxylic acids
Functional groups
Amines
Fluorescence
Color
Derivatives
Proteins

Keywords

  • Dimyristoyl phosphatidylcholine (DMPC)
  • Label-free biosensor
  • Microarray
  • Polydiacetylene

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Cite this

Kim, K. W., Park, M. K., Choi, H., Ahn, D. J., & Oh, M-K. (2010). Immobilized polydiacetylene vesicle for label-free biosensor. In 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010 (pp. 865-868). [5592171] https://doi.org/10.1109/NEMS.2010.5592171

Immobilized polydiacetylene vesicle for label-free biosensor. / Kim, Kyung Woo; Park, Moo Kyung; Choi, Hyun; Ahn, Dong June; Oh, Min-Kyu.

2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010. 2010. p. 865-868 5592171.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kim, KW, Park, MK, Choi, H, Ahn, DJ & Oh, M-K 2010, Immobilized polydiacetylene vesicle for label-free biosensor. in 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010., 5592171, pp. 865-868, 5th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010, Xiamen, China, 10/1/20. https://doi.org/10.1109/NEMS.2010.5592171
Kim KW, Park MK, Choi H, Ahn DJ, Oh M-K. Immobilized polydiacetylene vesicle for label-free biosensor. In 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010. 2010. p. 865-868. 5592171 https://doi.org/10.1109/NEMS.2010.5592171
Kim, Kyung Woo ; Park, Moo Kyung ; Choi, Hyun ; Ahn, Dong June ; Oh, Min-Kyu. / Immobilized polydiacetylene vesicle for label-free biosensor. 2010 IEEE 5th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2010. 2010. pp. 865-868
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