Abstract
The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.
| Original language | English |
|---|---|
| Pages (from-to) | 271-283 |
| Number of pages | 13 |
| Journal | The Korean journal of parasitology |
| Volume | 44 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2006 Dec 1 |
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ASJC Scopus subject areas
- Parasitology
- Infectious Diseases
Cite this
Immune reactions and allergy in experimental anisakiasis. / Cho, Sung-Weon; Lee, Haneul Nari.
In: The Korean journal of parasitology, Vol. 44, No. 4, 01.12.2006, p. 271-283.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Immune reactions and allergy in experimental anisakiasis.
AU - Cho, Sung-Weon
AU - Lee, Haneul Nari
PY - 2006/12/1
Y1 - 2006/12/1
N2 - The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.
AB - The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.
UR - http://www.scopus.com/inward/record.url?scp=39049193709&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=39049193709&partnerID=8YFLogxK
U2 - 10.3347/kjp.2006.44.4.271
DO - 10.3347/kjp.2006.44.4.271
M3 - Review article
C2 - 17170569
AN - SCOPUS:39049193709
VL - 44
SP - 271
EP - 283
JO - Korean Journal of Parasitology
JF - Korean Journal of Parasitology
SN - 0023-4001
IS - 4
ER -