Immune reactions and allergy in experimental anisakiasis.

Sung-Weon Cho, Haneul Nari Lee

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.

Original languageEnglish
Pages (from-to)271-283
Number of pages13
JournalThe Korean journal of parasitology
Volume44
Issue number4
DOIs
Publication statusPublished - 2006 Dec 1

Fingerprint

Anisakiasis
Hypersensitivity
Anisakis
Antibody Formation
Larva
Infection
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Immune reactions and allergy in experimental anisakiasis. / Cho, Sung-Weon; Lee, Haneul Nari.

In: The Korean journal of parasitology, Vol. 44, No. 4, 01.12.2006, p. 271-283.

Research output: Contribution to journalReview article

@article{3e5258db85b9492da0d02757269f5354,
title = "Immune reactions and allergy in experimental anisakiasis.",
abstract = "The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.",
author = "Sung-Weon Cho and Lee, {Haneul Nari}",
year = "2006",
month = "12",
day = "1",
doi = "10.3347/kjp.2006.44.4.271",
language = "English",
volume = "44",
pages = "271--283",
journal = "Korean Journal of Parasitology",
issn = "0023-4001",
publisher = "Korean Journal of Parasitology",
number = "4",

}

TY - JOUR

T1 - Immune reactions and allergy in experimental anisakiasis.

AU - Cho, Sung-Weon

AU - Lee, Haneul Nari

PY - 2006/12/1

Y1 - 2006/12/1

N2 - The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.

AB - The third-stage larvae (L3) of the parasitic nematode, Anisakis simplex, have been implicated in the induction of hyperimmune allergic reactions in orally infected humans. In this work, we have conducted a review of an investigation into immune reactions occurring in animals experimentally infected with A. simplex L3. The patterns of serum antibody productions in the experimental animals against excretory-secretory products (ESP) of A. simplex L3 contributed to our current knowledge regarding specific humoral immune reactions in humans. In our review, we were able to determine that L3 infection of experimental animals may constitute a good model system for further exploration of immune mechanisms and allergy in anisakiasis of humans.

UR - http://www.scopus.com/inward/record.url?scp=39049193709&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39049193709&partnerID=8YFLogxK

U2 - 10.3347/kjp.2006.44.4.271

DO - 10.3347/kjp.2006.44.4.271

M3 - Review article

C2 - 17170569

AN - SCOPUS:39049193709

VL - 44

SP - 271

EP - 283

JO - Korean Journal of Parasitology

JF - Korean Journal of Parasitology

SN - 0023-4001

IS - 4

ER -