Immunologic research in kidney ischemia/reperfusion injury at Johns Hopkins University

Gang Jee Ko, Asif Zakaria, Karl L. Womer, Hamid Rabb

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Abstracts: Kidney ischemia/reperfusion injury (IRI) is a common and serious problem in hospitalized patients. Immune cell trafficking and leukocyte-endothelial adhesion potentiate kidney IRI. An important immunomodulatory role of T lymphocytes has been elucidated in IRI. Regulatory T cells are a lymphocyte subset that has recently been demonstrated to perform a protective role both in early injury from IRI as well as in later repair. The immune system also participates in distant organ effects during kidney IRI. Studies focusing on immune aspects of kidney IRI have enabled the discovery of promising novel therapeutic and diagnostic approaches.

Original languageEnglish
Pages (from-to)78-85
Number of pages8
JournalImmunologic Research
Volume47
Issue number1-3
DOIs
Publication statusPublished - 2010 Jul 1
Externally publishedYes

Fingerprint

Reperfusion Injury
Kidney
Research
Lymphocyte Subsets
Regulatory T-Lymphocytes
Immune System
Leukocytes
T-Lymphocytes
Wounds and Injuries

Keywords

  • Acute kidney injury
  • Inflammation
  • Ischemia/reperfusion injury

ASJC Scopus subject areas

  • Immunology
  • Medicine(all)

Cite this

Immunologic research in kidney ischemia/reperfusion injury at Johns Hopkins University. / Ko, Gang Jee; Zakaria, Asif; Womer, Karl L.; Rabb, Hamid.

In: Immunologic Research, Vol. 47, No. 1-3, 01.07.2010, p. 78-85.

Research output: Contribution to journalReview article

Ko, Gang Jee ; Zakaria, Asif ; Womer, Karl L. ; Rabb, Hamid. / Immunologic research in kidney ischemia/reperfusion injury at Johns Hopkins University. In: Immunologic Research. 2010 ; Vol. 47, No. 1-3. pp. 78-85.
@article{57b106b0f0954a9aaf9ec59d66d50715,
title = "Immunologic research in kidney ischemia/reperfusion injury at Johns Hopkins University",
abstract = "Abstracts: Kidney ischemia/reperfusion injury (IRI) is a common and serious problem in hospitalized patients. Immune cell trafficking and leukocyte-endothelial adhesion potentiate kidney IRI. An important immunomodulatory role of T lymphocytes has been elucidated in IRI. Regulatory T cells are a lymphocyte subset that has recently been demonstrated to perform a protective role both in early injury from IRI as well as in later repair. The immune system also participates in distant organ effects during kidney IRI. Studies focusing on immune aspects of kidney IRI have enabled the discovery of promising novel therapeutic and diagnostic approaches.",
keywords = "Acute kidney injury, Inflammation, Ischemia/reperfusion injury",
author = "Ko, {Gang Jee} and Asif Zakaria and Womer, {Karl L.} and Hamid Rabb",
year = "2010",
month = "7",
day = "1",
doi = "10.1007/s12026-009-8140-7",
language = "English",
volume = "47",
pages = "78--85",
journal = "Immunologic Research",
issn = "0257-277X",
publisher = "Humana Press",
number = "1-3",

}

TY - JOUR

T1 - Immunologic research in kidney ischemia/reperfusion injury at Johns Hopkins University

AU - Ko, Gang Jee

AU - Zakaria, Asif

AU - Womer, Karl L.

AU - Rabb, Hamid

PY - 2010/7/1

Y1 - 2010/7/1

N2 - Abstracts: Kidney ischemia/reperfusion injury (IRI) is a common and serious problem in hospitalized patients. Immune cell trafficking and leukocyte-endothelial adhesion potentiate kidney IRI. An important immunomodulatory role of T lymphocytes has been elucidated in IRI. Regulatory T cells are a lymphocyte subset that has recently been demonstrated to perform a protective role both in early injury from IRI as well as in later repair. The immune system also participates in distant organ effects during kidney IRI. Studies focusing on immune aspects of kidney IRI have enabled the discovery of promising novel therapeutic and diagnostic approaches.

AB - Abstracts: Kidney ischemia/reperfusion injury (IRI) is a common and serious problem in hospitalized patients. Immune cell trafficking and leukocyte-endothelial adhesion potentiate kidney IRI. An important immunomodulatory role of T lymphocytes has been elucidated in IRI. Regulatory T cells are a lymphocyte subset that has recently been demonstrated to perform a protective role both in early injury from IRI as well as in later repair. The immune system also participates in distant organ effects during kidney IRI. Studies focusing on immune aspects of kidney IRI have enabled the discovery of promising novel therapeutic and diagnostic approaches.

KW - Acute kidney injury

KW - Inflammation

KW - Ischemia/reperfusion injury

UR - http://www.scopus.com/inward/record.url?scp=77953957887&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953957887&partnerID=8YFLogxK

U2 - 10.1007/s12026-009-8140-7

DO - 10.1007/s12026-009-8140-7

M3 - Review article

C2 - 20082154

AN - SCOPUS:77953957887

VL - 47

SP - 78

EP - 85

JO - Immunologic Research

JF - Immunologic Research

SN - 0257-277X

IS - 1-3

ER -