Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients

Chi Min Park, Younsuck Koh, Kyeongman Jeon, Sungwon Na, Chae Man Lim, Won Il Choi, Young Joo Lee, Seok Chan Kim, Gyu Rak Chon, Je Hyeong Kim, Jae Yeol Kim, Jaemin Lim, Chin Kook Rhee, Sunghoon Park, Ho Cheol Kim, Jin Hwa Lee, Ji Hyun Lee, Jisook Park, Juhee Cho, Shin Ok KohGee Young Suh, So Yeon Lim, Sang Bum Hong, Jin Won Huh, Suk Kyung Hong, Won Il Choi, Kwang Joo Park, Chan Kwon Park, Ick Hee Kim, Ho Cheol Kim, Hyun Lee, Jae Hwa Cho

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (. P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.

Original languageEnglish
Pages (from-to)409-413
Number of pages5
JournalJournal of Critical Care
Volume29
Issue number3
DOIs
Publication statusPublished - 2014 Jan 1

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Hospital Mortality
Critical Illness
Confidence Intervals
Intensive Care Units
Cohort Studies
Logistic Models
Retrospective Studies
Odds Ratio
Population
Neoplasms

Keywords

  • Hospital mortality
  • Intensive care
  • Performance status
  • Prognosis

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients. / Park, Chi Min; Koh, Younsuck; Jeon, Kyeongman; Na, Sungwon; Lim, Chae Man; Choi, Won Il; Lee, Young Joo; Kim, Seok Chan; Chon, Gyu Rak; Kim, Je Hyeong; Kim, Jae Yeol; Lim, Jaemin; Rhee, Chin Kook; Park, Sunghoon; Kim, Ho Cheol; Lee, Jin Hwa; Lee, Ji Hyun; Park, Jisook; Cho, Juhee; Koh, Shin Ok; Suh, Gee Young; Lim, So Yeon; Hong, Sang Bum; Huh, Jin Won; Hong, Suk Kyung; Choi, Won Il; Park, Kwang Joo; Park, Chan Kwon; Kim, Ick Hee; Kim, Ho Cheol; Lee, Hyun; Cho, Jae Hwa.

In: Journal of Critical Care, Vol. 29, No. 3, 01.01.2014, p. 409-413.

Research output: Contribution to journalArticle

Park, CM, Koh, Y, Jeon, K, Na, S, Lim, CM, Choi, WI, Lee, YJ, Kim, SC, Chon, GR, Kim, JH, Kim, JY, Lim, J, Rhee, CK, Park, S, Kim, HC, Lee, JH, Lee, JH, Park, J, Cho, J, Koh, SO, Suh, GY, Lim, SY, Hong, SB, Huh, JW, Hong, SK, Choi, WI, Park, KJ, Park, CK, Kim, IH, Kim, HC, Lee, H & Cho, JH 2014, 'Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients', Journal of Critical Care, vol. 29, no. 3, pp. 409-413. https://doi.org/10.1016/j.jcrc.2014.01.016
Park, Chi Min ; Koh, Younsuck ; Jeon, Kyeongman ; Na, Sungwon ; Lim, Chae Man ; Choi, Won Il ; Lee, Young Joo ; Kim, Seok Chan ; Chon, Gyu Rak ; Kim, Je Hyeong ; Kim, Jae Yeol ; Lim, Jaemin ; Rhee, Chin Kook ; Park, Sunghoon ; Kim, Ho Cheol ; Lee, Jin Hwa ; Lee, Ji Hyun ; Park, Jisook ; Cho, Juhee ; Koh, Shin Ok ; Suh, Gee Young ; Lim, So Yeon ; Hong, Sang Bum ; Huh, Jin Won ; Hong, Suk Kyung ; Choi, Won Il ; Park, Kwang Joo ; Park, Chan Kwon ; Kim, Ick Hee ; Kim, Ho Cheol ; Lee, Hyun ; Cho, Jae Hwa. / Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients. In: Journal of Critical Care. 2014 ; Vol. 29, No. 3. pp. 409-413.
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AU - Park, Chi Min

AU - Koh, Younsuck

AU - Jeon, Kyeongman

AU - Na, Sungwon

AU - Lim, Chae Man

AU - Choi, Won Il

AU - Lee, Young Joo

AU - Kim, Seok Chan

AU - Chon, Gyu Rak

AU - Kim, Je Hyeong

AU - Kim, Jae Yeol

AU - Lim, Jaemin

AU - Rhee, Chin Kook

AU - Park, Sunghoon

AU - Kim, Ho Cheol

AU - Lee, Jin Hwa

AU - Lee, Ji Hyun

AU - Park, Jisook

AU - Cho, Juhee

AU - Koh, Shin Ok

AU - Suh, Gee Young

AU - Lim, So Yeon

AU - Hong, Sang Bum

AU - Huh, Jin Won

AU - Hong, Suk Kyung

AU - Choi, Won Il

AU - Park, Kwang Joo

AU - Park, Chan Kwon

AU - Kim, Ick Hee

AU - Kim, Ho Cheol

AU - Lee, Hyun

AU - Cho, Jae Hwa

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (. P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.

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KW - Hospital mortality

KW - Intensive care

KW - Performance status

KW - Prognosis

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