Impact of non-compliant balloons on long-term clinical outcomes in coronary bifurcation lesions

Results from the COBIS (COronary BIfurcation Stent) II registry

Taek Kyu Park, Jae Hwan Lee, Young Bin Song, Jin Ok Jeong, Joo Yong Hahn, Jeong Hoon Yang, Seung Hyuk Choi, Jin Ho Choi, Sang Hoon Lee, Myung Ho Jeong, Hyo Soo Kim, Ju Hyeon Oh, Cheol Woong Yu, Seung-Woon Rha, Yangsoo Jang, Jung Han Yoon, Seung Jea Tahk, Ki Bae Seung, Jong Seon Park, Hyeon Cheol Gwon

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aims: Non-compliant balloons provide uniform radial force along the vessel wall at any inflation pressure. As a result, the use of non-compliant balloons may reduce side branch complications and optimise stent deployment. We sought to investigate the impact of non-compliant balloons on the long-term clinical outcomes of patients undergoing a coronary bifurcation intervention. Methods and results: A total of 2,897 patients treated with drug-eluting stents for bifurcation lesions were enrolled. Non-compliant balloons were used in 752 patients (26%). During a median three-year follow-up, major adverse cardiac events (MACE: cardiac death, myocardial infarction, or target lesion revascularisation) occurred less frequently in the non-compliant balloon group than in the compliant balloon group (8.2% versus 10.9%; p=0.03). After propensity score matching (710 pairs), the use of non-compliant balloons resulted in a lower rate of side branch dissection (0.1% versus 1.1%; p=0.046) and a higher rate of procedural success (79.0% versus 73.9%; p=0.01). The use of non-compliant balloons was associated with a lower risk of MACE (HR 0.64, 95% CI: 0.46-0.91; p=0.01) and cardiac death (HR 0.14, 95% CI: 0.03-0.64; p=0.01). Conclusions: The use of non-compliant balloons was associated with favourable procedural and longterm clinical outcomes in patients receiving coronary bifurcation intervention.

Original languageEnglish
Pages (from-to)456-464
Number of pages9
JournalEuroIntervention
Volume12
Issue number4
DOIs
Publication statusPublished - 2016 Jul 1

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Stents
Registries
Propensity Score
Drug-Eluting Stents
Economic Inflation
Dissection
Myocardial Infarction
Pressure

Keywords

  • Angioplasty
  • Coronary bifurcation
  • Non-compliant balloon

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Impact of non-compliant balloons on long-term clinical outcomes in coronary bifurcation lesions : Results from the COBIS (COronary BIfurcation Stent) II registry. / Park, Taek Kyu; Lee, Jae Hwan; Song, Young Bin; Jeong, Jin Ok; Hahn, Joo Yong; Yang, Jeong Hoon; Choi, Seung Hyuk; Choi, Jin Ho; Lee, Sang Hoon; Jeong, Myung Ho; Kim, Hyo Soo; Oh, Ju Hyeon; Yu, Cheol Woong; Rha, Seung-Woon; Jang, Yangsoo; Yoon, Jung Han; Tahk, Seung Jea; Seung, Ki Bae; Park, Jong Seon; Gwon, Hyeon Cheol.

In: EuroIntervention, Vol. 12, No. 4, 01.07.2016, p. 456-464.

Research output: Contribution to journalArticle

Park, TK, Lee, JH, Song, YB, Jeong, JO, Hahn, JY, Yang, JH, Choi, SH, Choi, JH, Lee, SH, Jeong, MH, Kim, HS, Oh, JH, Yu, CW, Rha, S-W, Jang, Y, Yoon, JH, Tahk, SJ, Seung, KB, Park, JS & Gwon, HC 2016, 'Impact of non-compliant balloons on long-term clinical outcomes in coronary bifurcation lesions: Results from the COBIS (COronary BIfurcation Stent) II registry', EuroIntervention, vol. 12, no. 4, pp. 456-464. https://doi.org/10.4244/EIJV12I4A79
Park, Taek Kyu ; Lee, Jae Hwan ; Song, Young Bin ; Jeong, Jin Ok ; Hahn, Joo Yong ; Yang, Jeong Hoon ; Choi, Seung Hyuk ; Choi, Jin Ho ; Lee, Sang Hoon ; Jeong, Myung Ho ; Kim, Hyo Soo ; Oh, Ju Hyeon ; Yu, Cheol Woong ; Rha, Seung-Woon ; Jang, Yangsoo ; Yoon, Jung Han ; Tahk, Seung Jea ; Seung, Ki Bae ; Park, Jong Seon ; Gwon, Hyeon Cheol. / Impact of non-compliant balloons on long-term clinical outcomes in coronary bifurcation lesions : Results from the COBIS (COronary BIfurcation Stent) II registry. In: EuroIntervention. 2016 ; Vol. 12, No. 4. pp. 456-464.
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abstract = "Aims: Non-compliant balloons provide uniform radial force along the vessel wall at any inflation pressure. As a result, the use of non-compliant balloons may reduce side branch complications and optimise stent deployment. We sought to investigate the impact of non-compliant balloons on the long-term clinical outcomes of patients undergoing a coronary bifurcation intervention. Methods and results: A total of 2,897 patients treated with drug-eluting stents for bifurcation lesions were enrolled. Non-compliant balloons were used in 752 patients (26{\%}). During a median three-year follow-up, major adverse cardiac events (MACE: cardiac death, myocardial infarction, or target lesion revascularisation) occurred less frequently in the non-compliant balloon group than in the compliant balloon group (8.2{\%} versus 10.9{\%}; p=0.03). After propensity score matching (710 pairs), the use of non-compliant balloons resulted in a lower rate of side branch dissection (0.1{\%} versus 1.1{\%}; p=0.046) and a higher rate of procedural success (79.0{\%} versus 73.9{\%}; p=0.01). The use of non-compliant balloons was associated with a lower risk of MACE (HR 0.64, 95{\%} CI: 0.46-0.91; p=0.01) and cardiac death (HR 0.14, 95{\%} CI: 0.03-0.64; p=0.01). Conclusions: The use of non-compliant balloons was associated with favourable procedural and longterm clinical outcomes in patients receiving coronary bifurcation intervention.",
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T2 - Results from the COBIS (COronary BIfurcation Stent) II registry

AU - Park, Taek Kyu

AU - Lee, Jae Hwan

AU - Song, Young Bin

AU - Jeong, Jin Ok

AU - Hahn, Joo Yong

AU - Yang, Jeong Hoon

AU - Choi, Seung Hyuk

AU - Choi, Jin Ho

AU - Lee, Sang Hoon

AU - Jeong, Myung Ho

AU - Kim, Hyo Soo

AU - Oh, Ju Hyeon

AU - Yu, Cheol Woong

AU - Rha, Seung-Woon

AU - Jang, Yangsoo

AU - Yoon, Jung Han

AU - Tahk, Seung Jea

AU - Seung, Ki Bae

AU - Park, Jong Seon

AU - Gwon, Hyeon Cheol

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Aims: Non-compliant balloons provide uniform radial force along the vessel wall at any inflation pressure. As a result, the use of non-compliant balloons may reduce side branch complications and optimise stent deployment. We sought to investigate the impact of non-compliant balloons on the long-term clinical outcomes of patients undergoing a coronary bifurcation intervention. Methods and results: A total of 2,897 patients treated with drug-eluting stents for bifurcation lesions were enrolled. Non-compliant balloons were used in 752 patients (26%). During a median three-year follow-up, major adverse cardiac events (MACE: cardiac death, myocardial infarction, or target lesion revascularisation) occurred less frequently in the non-compliant balloon group than in the compliant balloon group (8.2% versus 10.9%; p=0.03). After propensity score matching (710 pairs), the use of non-compliant balloons resulted in a lower rate of side branch dissection (0.1% versus 1.1%; p=0.046) and a higher rate of procedural success (79.0% versus 73.9%; p=0.01). The use of non-compliant balloons was associated with a lower risk of MACE (HR 0.64, 95% CI: 0.46-0.91; p=0.01) and cardiac death (HR 0.14, 95% CI: 0.03-0.64; p=0.01). Conclusions: The use of non-compliant balloons was associated with favourable procedural and longterm clinical outcomes in patients receiving coronary bifurcation intervention.

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KW - Angioplasty

KW - Coronary bifurcation

KW - Non-compliant balloon

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