Implementation of a biocircuit implants for neurotransmitter release during neuro-stimulation

Suw Young Ly, DalWoong Choi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Neurotransmitter assay of epinephrine (EP) was sought using a modified carbon nanotube paste electrode (PE). Using optimum conditions, cyclic voltammetry (CV) and the square wave (SW) stripping voltammetric working ranges were attained to 10-100 mgL-1 (CV) and 20-140 ngL-1 (SW). The relative standard deviation of 0.0549 (n=15) was obtained at 20.0 mgL -1 EP constant. Here, the analytical detection limit (S/N) was reached with 4.60 ngL-1 (2.5×10-11 molL-1) EP. The hand-made electrode was implanted into the in-vivo brain core of the animals and was used in chronoamperometric neuro detection. The results obtained are applicable in neuro sensing, physiological control, and other neuroscience fields.

Original languageEnglish
Pages (from-to)238-246
Number of pages9
JournalCurrent Neurovascular Research
Volume10
Issue number3
DOIs
Publication statusPublished - 2013 Aug 1

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Keywords

  • Brain
  • Electrochemical
  • Epinephrine
  • In vivo
  • Interface
  • Neuro sens

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience
  • Cellular and Molecular Neuroscience

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