Improved physicochemical properties and hepatic protection of Maillard reaction products derived from fish protein hydrolysates and ribose

Sung Yong Yang, Sanghoon Lee, Min Cheol Pyo, Hyeonjin Jeon, Yoonsook Kim, Kwang Won Lee

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

High amounts of waste products generated from fish-processing need to be disposed of despite their potential nutritional value. A variety of methods, such as enzymatic hydrolysis, have been developed for these byproducts. In the current study, we investigated the physicochemical, biological and antioxidative properties of fish protein hydrolysates (FPH) conjugated with ribose through the Maillard reaction. These glycated conjugates of FPH (GFPH) had more viscous rheological properties than FPH and exhibited higher heat, emulsification and foaming stability. They also protected liver HepG2 cells against t-BHP-induced oxidative stress with enhanced glutathione synthesis in vitro. Furthermore, it was shown that GFPH induced upregulation of phase II enzyme expression, such as that of HO-1 and γ-GCL, via nuclear translocation of Nrf2 and phosphorylation of ERK. Taken together, these results demonstrate the potential of GFPH for use as a functional food ingredient with improved rheological and antioxidative properties.

Original languageEnglish
Pages (from-to)1979-1988
Number of pages10
JournalFood Chemistry
Volume221
DOIs
Publication statusPublished - 2017 Apr 15

Fingerprint

fish protein hydrolysate
Fish Proteins
Protein Hydrolysates
Maillard Reaction
Maillard reaction products
Ribose
ribose
Reaction products
physicochemical properties
liver
Liver
Waste Products
fish processing
Functional Food
Phosphorylation
foaming
Enzymatic hydrolysis
Oxidative stress
Emulsification
Nutritive Value

Keywords

  • Fish protein hydrolysate
  • Hepatic protection
  • Maillard reaction
  • Nrf2 transcription factor
  • Physicochemical property

ASJC Scopus subject areas

  • Analytical Chemistry
  • Food Science
  • Medicine(all)

Cite this

Improved physicochemical properties and hepatic protection of Maillard reaction products derived from fish protein hydrolysates and ribose. / Yang, Sung Yong; Lee, Sanghoon; Pyo, Min Cheol; Jeon, Hyeonjin; Kim, Yoonsook; Lee, Kwang Won.

In: Food Chemistry, Vol. 221, 15.04.2017, p. 1979-1988.

Research output: Contribution to journalArticle

Yang, Sung Yong ; Lee, Sanghoon ; Pyo, Min Cheol ; Jeon, Hyeonjin ; Kim, Yoonsook ; Lee, Kwang Won. / Improved physicochemical properties and hepatic protection of Maillard reaction products derived from fish protein hydrolysates and ribose. In: Food Chemistry. 2017 ; Vol. 221. pp. 1979-1988.
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