In-situ fabrication of porous hydroxyapatite (HA) scaffolds with dense shells by freezing HA/camphene slurry

Byung H. Yoon, Chee Sung Park, Hyoun E. Kim, Young-Hag Koh

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We fabricated a novel type of porous HA scaffold with a dense shell/porous core structure by freezing a hydroxyapatite (HA)/camphene slurry in-situ. During freezing, the camphene dendrites from the mold wall grew 2-dimensionally by pushing the HA particles into the remaining slurry, which resulted in the formation of a camphene layer/concentrated HA particles layer as the surrounding skin of the sample. After removing the frozen camphene and sintering the HA walls at 1250 °C for 3 h, a dense shell integrated with a porous core was formed in-situ. We prepared two types of porous HA scaffold, a porous HA cylinder with a dense shell and a 3-D HA scaffold, consisting of periodic HA networks with a dense shell/porous core structure. These novel scaffolds would be expected to have improved mechanical integrity due to the use of a dense shell, as well as efficient bone ingrowth inside pores formed in a porous core.

Original languageEnglish
Pages (from-to)1700-1703
Number of pages4
JournalMaterials Letters
Volume62
Issue number10-11
DOIs
Publication statusPublished - 2008 Apr 15

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Keywords

  • Dense
  • Freeze casting
  • Hydroxyapatite
  • Porous
  • Strength

ASJC Scopus subject areas

  • Materials Science(all)

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