In vitro 3-dimensional microfluidic assay for studying invasion of cholangiocarcinoma

Jihee Won, Youngkyu Cho, Yesl Jun, Jhangho Pak, Seok Chung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Clonorchis sinensis (C. sinensis) is prevalent worm parasite in many East Asian countries including Japan, Korea and China. And it is classified as a group I biological carcinogen of human cholangiocarcinorma (CCA) in 2009 by International Agency for Research on Cancer (IARC) [1, 2]. Although many reports were suggested that infestation of the C. sinensis is associated with prognosis of CCA, the specific effect of the C. sinensis on CCA is poorly understood. Here we investigated the invasiveness of the CCA influenced by stimulus of C. sinensis using 3D microfluidic culture system.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages1711-1713
Number of pages3
ISBN (Electronic)9781510897571
Publication statusPublished - 2018 Jan 1
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: 2018 Nov 112018 Nov 15

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume3

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
CountryTaiwan, Province of China
CityKaohsiung
Period18/11/1118/11/15

Keywords

  • Cancer invasion
  • Cancer migration
  • Cholangiocarcinoma
  • Clonorchis sinensis
  • Microfluidic chip

ASJC Scopus subject areas

  • Chemistry(all)
  • Bioengineering
  • Chemical Engineering (miscellaneous)
  • Control and Systems Engineering

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  • Cite this

    Won, J., Cho, Y., Jun, Y., Pak, J., & Chung, S. (2018). In vitro 3-dimensional microfluidic assay for studying invasion of cholangiocarcinoma. In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 (pp. 1711-1713). (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; Vol. 3). Chemical and Biological Microsystems Society.