In vitro dynamic degradation behavior of new magnesium alloy for orthopedic applications

Gui Fu Yang, Yu Chan Kim, Hyung Seop Han, Gwang Chul Lee, Hyun Kwang Seok, Jae-chul Lee

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

We report on methodologies for use in the design of a biodegradable Mg alloy appropriate for load-bearing but temporary orthopedic implant applications. Comparative studies of Mg-5Ca and Mg-5Ca-1Zn were conducted to explore the effects of a combination of minor alloying and hot extrusion, on the alloy's mechanical properties and corrosion resistance. The extruded Mg-5Ca-1Zn exhibited high ultimate compressive strength of 385 MPa and suffered no significant structural degradation even after immersion in simulated body fluid for 30 days. Mg-5Ca-1Zn alloy showed the mechanical strength and controlled corrosion rate to be considered as an ideal candidate for biodegradable orthopedic implant material.

Original languageEnglish
Pages (from-to)807-815
Number of pages9
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume103
Issue number4
DOIs
Publication statusPublished - 2015 May 1

Keywords

  • biodegradation
  • magnesium
  • mechanical properties
  • SEM
  • zinc

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials

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