Abstract
We report on methodologies for use in the design of a biodegradable Mg alloy appropriate for load-bearing but temporary orthopedic implant applications. Comparative studies of Mg-5Ca and Mg-5Ca-1Zn were conducted to explore the effects of a combination of minor alloying and hot extrusion, on the alloy's mechanical properties and corrosion resistance. The extruded Mg-5Ca-1Zn exhibited high ultimate compressive strength of 385 MPa and suffered no significant structural degradation even after immersion in simulated body fluid for 30 days. Mg-5Ca-1Zn alloy showed the mechanical strength and controlled corrosion rate to be considered as an ideal candidate for biodegradable orthopedic implant material.
| Original language | English |
|---|---|
| Pages (from-to) | 807-815 |
| Number of pages | 9 |
| Journal | Journal of Biomedical Materials Research - Part B Applied Biomaterials |
| Volume | 103 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2015 May 1 |
Keywords
- biodegradation
- magnesium
- mechanical properties
- SEM
- zinc
ASJC Scopus subject areas
- Biomedical Engineering
- Biomaterials
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Cite this
Yang, G. F., Kim, Y. C., Han, H. S., Lee, G. C., Seok, H. K., & Lee, J. (2015). In vitro dynamic degradation behavior of new magnesium alloy for orthopedic applications. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 103(4), 807-815. https://doi.org/10.1002/jbm.b.33259