In vitro evaluation of betafoam, a new polyurethane foam dressing

Jae A. Jung, Seung-Kyu Han, Seong-Ho Jeong, Eun-Sang Dhong, Kang Gyun Park, Woo-Kyung Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

BACKGROUND: A new polyurethane foam dressing impregnated with 3% povidone-iodine (Betafoam; Genewell, Seoul, Korea) was recently developed based on the hypothesis that its physical properties, including improved moisture-retention capacity and antimicrobial activity, are at least as good as those achieved with the current foam dressings that contain silver, but also associated with reduced cost and cytotoxicity to host cells. The purpose of this in vitro study was to evaluate the efficacy of Betafoam by comparing its physical properties, antimicrobial activity, and cytotoxicity with those of 3 silver foam dressings (Allevyn-Ag [Smith & Nephew, Hull, United Kingdom]; Mepilex-Ag [Mö lnlycke Health Care, Gothenburg, Sweden]; and PolyMem-Ag [Ferris MFG Corp, Burr Ridge, Illinois]) used worldwide. METHODS: This study measured each dressing's pore size, fluid absorption time, fluid absorption capacity, fluid retention capacity, antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa, and cytotoxicity to mouse fibroblasts. RESULTS: Betafoam had the smallest pore size, the fastest fluid absorption time, greatest fluid absorption, and best retention capacities among the tested foam dressings. Antimicrobial activity was not significantly different among the dressings. However, Betafoam also demonstrated the lowest cytotoxicity to the fibroblasts. CONCLUSIONS: Betafoam may result not only in desirable rapid regulation of exudation but also antimicrobial activity with minimal cytotoxicity to host cells that are key requirements for wound healing.

Original languageEnglish
Pages (from-to)262-270
Number of pages9
JournalAdvances in Skin and Wound Care
Volume30
Issue number6
DOIs
Publication statusPublished - 2017 Jun 1

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Keywords

  • Antimicrobial activity
  • Betafoam
  • Cytotoxicity
  • Exudate
  • Polyurethane foam dressing
  • Povidone-iodine
  • Wound healing

ASJC Scopus subject areas

  • Dermatology
  • Advanced and Specialised Nursing

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