In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Heebeom Koo, Hyejung Lee, Sojin Lee, Kyung Hyun Min, Min Sang Kim, Doo Sung Lee, Yongseok Choi, Ick Chan Kwon, Kwang Meyung Kim, Seo Young Jeong

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142 Citations (Scopus)

Abstract

We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

Original languageEnglish
Pages (from-to)5668-5670
Number of pages3
JournalChemical Communications
Volume46
Issue number31
DOIs
Publication statusPublished - 2010 Aug 21

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ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Koo, H., Lee, H., Lee, S., Min, K. H., Kim, M. S., Lee, D. S., Choi, Y., Kwon, I. C., Kim, K. M., & Jeong, S. Y. (2010). In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. Chemical Communications, 46(31), 5668-5670. https://doi.org/10.1039/c0cc01413c