In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Heebeom Koo, Hyejung Lee, Sojin Lee, Kyung Hyun Min, Min Sang Kim, Doo Sung Lee, Yongseok Choi, Ick Chan Kwon, Kwang Meyung Kim, Seo Young Jeong

Research output: Contribution to journalArticle

136 Citations (Scopus)

Abstract

We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

Original languageEnglish
Pages (from-to)5668-5670
Number of pages3
JournalChemical Communications
Volume46
Issue number31
DOIs
Publication statusPublished - 2010 Aug 21

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Micellization
Photodynamic therapy
Oncology
Photochemotherapy
Micelles
Tumors
Neoplasms
Therapeutics
protoporphyrin IX

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Koo, H., Lee, H., Lee, S., Min, K. H., Kim, M. S., Lee, D. S., ... Jeong, S. Y. (2010). In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. Chemical Communications, 46(31), 5668-5670. https://doi.org/10.1039/c0cc01413c

In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. / Koo, Heebeom; Lee, Hyejung; Lee, Sojin; Min, Kyung Hyun; Kim, Min Sang; Lee, Doo Sung; Choi, Yongseok; Kwon, Ick Chan; Kim, Kwang Meyung; Jeong, Seo Young.

In: Chemical Communications, Vol. 46, No. 31, 21.08.2010, p. 5668-5670.

Research output: Contribution to journalArticle

Koo, H, Lee, H, Lee, S, Min, KH, Kim, MS, Lee, DS, Choi, Y, Kwon, IC, Kim, KM & Jeong, SY 2010, 'In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles', Chemical Communications, vol. 46, no. 31, pp. 5668-5670. https://doi.org/10.1039/c0cc01413c
Koo, Heebeom ; Lee, Hyejung ; Lee, Sojin ; Min, Kyung Hyun ; Kim, Min Sang ; Lee, Doo Sung ; Choi, Yongseok ; Kwon, Ick Chan ; Kim, Kwang Meyung ; Jeong, Seo Young. / In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. In: Chemical Communications. 2010 ; Vol. 46, No. 31. pp. 5668-5670.
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