Incidence and case fatality rates of community-acquired pneumonia and pneumococcal diseases among Korean adults: Catchment population-based analysis

Jung Yeon Heo, Yu Bin Seo, Wonseok Choi, Jacob Lee, Jin Gu Yoon, Saem Na Lee, Min Joo Choi, Ji Yun Noh, Jin Young Ahn, Hye Won Jeong, Hee-Jin Cheong, Woo Joo Kim, Hee Young Lee, Joon-Young Song

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background Pneumonia is a leading infectious cause of morbidity and mortality among adults. Pneumococcal pneumonia (PP) is the most common vaccine-preventable bacterial etiology of pneumonia. In this study, we estimated the incidence of community-acquired pneumonia (CAP) and pneumococcal diseases among Korean adults. Methods Clinical and microbiological databases from three hospitals were retrospectively reviewed to determine the incidence and case fatality rates of CAP and pneumococcal diseases in Korean adults aged 19 years from 2011 to 2014. Incidence and case fatality rates of CAP, PP and invasive pneumococcal diseases (IPD) were evaluated based on the catchment population. Catchment population was calculated using national health insurance data, estimating the proportion of patients with pneumonia that were medically attended at each hospital. Results Among 5,783 patients with medically attended CAP, 833 (14.4%) had PP. For IPD, a total of 91 culture-confirmed cases were identified. The overall incidence of CAP was 307.7 cases per 100,000 persons per year with an in-hospital mortality rate of 6.2%. The estimated annual incidence of pneumococcal pneumonia was 42.2–49.4 cases per 100,000 persons per year, increasing with age to >280 per 100,000 persons per year in older patients over 70 years. The annual incidence of IPD had a range of 4.1–6.5 cases per 100,000 persons per year. The overall case fatality rate for invasive pneumococcal diseases was 30.8% with the highest rate of 66.7% in patients over 80 years. Conclusion Over the study period, incidences of CAP, PP and IPD were consistently high, particularly in older people. These results provide baseline data to establish healthcare strategies and estimate their impact among Korean adults.

Original languageEnglish
Article numbere0194598
JournalPLoS One
Volume13
Issue number3
DOIs
Publication statusPublished - 2018 Mar 1

Fingerprint

Pneumococcal Pneumonia
Catchments
pneumonia
Pneumonia
incidence
Mortality
Incidence
Population
Health insurance
Bacterial Vaccines
Bacterial Pneumonia
National Health Programs
Hospital Mortality
Cohort Studies
Vaccines
Databases
Morbidity
Delivery of Health Care
health insurance

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Incidence and case fatality rates of community-acquired pneumonia and pneumococcal diseases among Korean adults : Catchment population-based analysis. / Heo, Jung Yeon; Seo, Yu Bin; Choi, Wonseok; Lee, Jacob; Yoon, Jin Gu; Lee, Saem Na; Choi, Min Joo; Noh, Ji Yun; Ahn, Jin Young; Jeong, Hye Won; Cheong, Hee-Jin; Kim, Woo Joo; Lee, Hee Young; Song, Joon-Young.

In: PLoS One, Vol. 13, No. 3, e0194598, 01.03.2018.

Research output: Contribution to journalArticle

Heo, Jung Yeon ; Seo, Yu Bin ; Choi, Wonseok ; Lee, Jacob ; Yoon, Jin Gu ; Lee, Saem Na ; Choi, Min Joo ; Noh, Ji Yun ; Ahn, Jin Young ; Jeong, Hye Won ; Cheong, Hee-Jin ; Kim, Woo Joo ; Lee, Hee Young ; Song, Joon-Young. / Incidence and case fatality rates of community-acquired pneumonia and pneumococcal diseases among Korean adults : Catchment population-based analysis. In: PLoS One. 2018 ; Vol. 13, No. 3.
@article{06614159b1bd4054a7b013aa56a372d2,
title = "Incidence and case fatality rates of community-acquired pneumonia and pneumococcal diseases among Korean adults: Catchment population-based analysis",
abstract = "Background Pneumonia is a leading infectious cause of morbidity and mortality among adults. Pneumococcal pneumonia (PP) is the most common vaccine-preventable bacterial etiology of pneumonia. In this study, we estimated the incidence of community-acquired pneumonia (CAP) and pneumococcal diseases among Korean adults. Methods Clinical and microbiological databases from three hospitals were retrospectively reviewed to determine the incidence and case fatality rates of CAP and pneumococcal diseases in Korean adults aged 19 years from 2011 to 2014. Incidence and case fatality rates of CAP, PP and invasive pneumococcal diseases (IPD) were evaluated based on the catchment population. Catchment population was calculated using national health insurance data, estimating the proportion of patients with pneumonia that were medically attended at each hospital. Results Among 5,783 patients with medically attended CAP, 833 (14.4{\%}) had PP. For IPD, a total of 91 culture-confirmed cases were identified. The overall incidence of CAP was 307.7 cases per 100,000 persons per year with an in-hospital mortality rate of 6.2{\%}. The estimated annual incidence of pneumococcal pneumonia was 42.2–49.4 cases per 100,000 persons per year, increasing with age to >280 per 100,000 persons per year in older patients over 70 years. The annual incidence of IPD had a range of 4.1–6.5 cases per 100,000 persons per year. The overall case fatality rate for invasive pneumococcal diseases was 30.8{\%} with the highest rate of 66.7{\%} in patients over 80 years. Conclusion Over the study period, incidences of CAP, PP and IPD were consistently high, particularly in older people. These results provide baseline data to establish healthcare strategies and estimate their impact among Korean adults.",
author = "Heo, {Jung Yeon} and Seo, {Yu Bin} and Wonseok Choi and Jacob Lee and Yoon, {Jin Gu} and Lee, {Saem Na} and Choi, {Min Joo} and Noh, {Ji Yun} and Ahn, {Jin Young} and Jeong, {Hye Won} and Hee-Jin Cheong and Kim, {Woo Joo} and Lee, {Hee Young} and Joon-Young Song",
year = "2018",
month = "3",
day = "1",
doi = "10.1371/journal.pone.0194598",
language = "English",
volume = "13",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "3",

}

TY - JOUR

T1 - Incidence and case fatality rates of community-acquired pneumonia and pneumococcal diseases among Korean adults

T2 - Catchment population-based analysis

AU - Heo, Jung Yeon

AU - Seo, Yu Bin

AU - Choi, Wonseok

AU - Lee, Jacob

AU - Yoon, Jin Gu

AU - Lee, Saem Na

AU - Choi, Min Joo

AU - Noh, Ji Yun

AU - Ahn, Jin Young

AU - Jeong, Hye Won

AU - Cheong, Hee-Jin

AU - Kim, Woo Joo

AU - Lee, Hee Young

AU - Song, Joon-Young

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Background Pneumonia is a leading infectious cause of morbidity and mortality among adults. Pneumococcal pneumonia (PP) is the most common vaccine-preventable bacterial etiology of pneumonia. In this study, we estimated the incidence of community-acquired pneumonia (CAP) and pneumococcal diseases among Korean adults. Methods Clinical and microbiological databases from three hospitals were retrospectively reviewed to determine the incidence and case fatality rates of CAP and pneumococcal diseases in Korean adults aged 19 years from 2011 to 2014. Incidence and case fatality rates of CAP, PP and invasive pneumococcal diseases (IPD) were evaluated based on the catchment population. Catchment population was calculated using national health insurance data, estimating the proportion of patients with pneumonia that were medically attended at each hospital. Results Among 5,783 patients with medically attended CAP, 833 (14.4%) had PP. For IPD, a total of 91 culture-confirmed cases were identified. The overall incidence of CAP was 307.7 cases per 100,000 persons per year with an in-hospital mortality rate of 6.2%. The estimated annual incidence of pneumococcal pneumonia was 42.2–49.4 cases per 100,000 persons per year, increasing with age to >280 per 100,000 persons per year in older patients over 70 years. The annual incidence of IPD had a range of 4.1–6.5 cases per 100,000 persons per year. The overall case fatality rate for invasive pneumococcal diseases was 30.8% with the highest rate of 66.7% in patients over 80 years. Conclusion Over the study period, incidences of CAP, PP and IPD were consistently high, particularly in older people. These results provide baseline data to establish healthcare strategies and estimate their impact among Korean adults.

AB - Background Pneumonia is a leading infectious cause of morbidity and mortality among adults. Pneumococcal pneumonia (PP) is the most common vaccine-preventable bacterial etiology of pneumonia. In this study, we estimated the incidence of community-acquired pneumonia (CAP) and pneumococcal diseases among Korean adults. Methods Clinical and microbiological databases from three hospitals were retrospectively reviewed to determine the incidence and case fatality rates of CAP and pneumococcal diseases in Korean adults aged 19 years from 2011 to 2014. Incidence and case fatality rates of CAP, PP and invasive pneumococcal diseases (IPD) were evaluated based on the catchment population. Catchment population was calculated using national health insurance data, estimating the proportion of patients with pneumonia that were medically attended at each hospital. Results Among 5,783 patients with medically attended CAP, 833 (14.4%) had PP. For IPD, a total of 91 culture-confirmed cases were identified. The overall incidence of CAP was 307.7 cases per 100,000 persons per year with an in-hospital mortality rate of 6.2%. The estimated annual incidence of pneumococcal pneumonia was 42.2–49.4 cases per 100,000 persons per year, increasing with age to >280 per 100,000 persons per year in older patients over 70 years. The annual incidence of IPD had a range of 4.1–6.5 cases per 100,000 persons per year. The overall case fatality rate for invasive pneumococcal diseases was 30.8% with the highest rate of 66.7% in patients over 80 years. Conclusion Over the study period, incidences of CAP, PP and IPD were consistently high, particularly in older people. These results provide baseline data to establish healthcare strategies and estimate their impact among Korean adults.

UR - http://www.scopus.com/inward/record.url?scp=85044998841&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044998841&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0194598

DO - 10.1371/journal.pone.0194598

M3 - Article

C2 - 29596444

AN - SCOPUS:85044998841

VL - 13

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 3

M1 - e0194598

ER -