Incidence and natural course of inflammatory bowel disease in Korea, 2006-2012: A nationwide population-based study

Hyun Jung Kim, Hoo Jae Hann, Sung No Hong, Kyoung Hoon Kim, Il Min Ahn, Ji Yang Song, Sang Hyuk Lee, Hyeong Sik Ahn

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Background: Although a rising trend in the incidence of inflammatory bowel disease (IBD) in Asia has been recognized, national-level, population-based studies are lacking. In this study, we investigate the epidemiological features and natural course of IBD in Korea, including incidence, bowel resection rates, survival, and cause of death. Methods: We analyzed the Rare Intractable Disease registration and Health Insurance Review and Assessment Services claims database, which include information on every patients with IBD diagnosed through uniform criteria from 2006 to 2012. Twenty-seven thousand four hundred nineteen patients with IBD newly diagnosed from 2006 to 2012 were traced to bowel resection, survival, and cause of death. Results: During study period, mean annual incidence for ulcerative colitis was 4.6 per 105 and for Crohn's disease (CD) was 3.2 per 105. Bowel resection rates at 1 and 5 years for patients with ulcerative colitis were 0.8% and 2.1%, respectively, and for patients with CD were 5.0% and 9.1%, respectively. Survival of patients with CD was lower than that of the general population, whereas patients with ulcerative colitis had similar survival. In patients with CD, mortality for colon cancer, lung cancer, and gastrointestinal disease was significantly increased compared with general population. Conclusions: Incidence of IBD found in our study is the highest in East Asia. Lower bowel resection rates and higher survival compared to those of Western nations suggest that the natural course of IBD may be different between East Asia and the West.

Original languageEnglish
Pages (from-to)623-630
Number of pages8
JournalInflammatory Bowel Diseases
Volume21
Issue number3
DOIs
Publication statusPublished - 2015 Jan 9

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Korea
Inflammatory Bowel Diseases
Incidence
Crohn Disease
Population
Ulcerative Colitis
Far East
Survival
Cause of Death
Lung Neoplasms
Survival Rate
Gastrointestinal Diseases
Health Insurance
Rare Diseases
Colonic Neoplasms
Lung Diseases
Databases
Mortality

Keywords

  • bowel resection
  • Crohn's disease
  • epidemiology
  • Korea
  • mortality
  • ulcerative colitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology

Cite this

Incidence and natural course of inflammatory bowel disease in Korea, 2006-2012 : A nationwide population-based study. / Kim, Hyun Jung; Hann, Hoo Jae; Hong, Sung No; Kim, Kyoung Hoon; Ahn, Il Min; Song, Ji Yang; Lee, Sang Hyuk; Ahn, Hyeong Sik.

In: Inflammatory Bowel Diseases, Vol. 21, No. 3, 09.01.2015, p. 623-630.

Research output: Contribution to journalArticle

Kim, Hyun Jung ; Hann, Hoo Jae ; Hong, Sung No ; Kim, Kyoung Hoon ; Ahn, Il Min ; Song, Ji Yang ; Lee, Sang Hyuk ; Ahn, Hyeong Sik. / Incidence and natural course of inflammatory bowel disease in Korea, 2006-2012 : A nationwide population-based study. In: Inflammatory Bowel Diseases. 2015 ; Vol. 21, No. 3. pp. 623-630.
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