Incidence of cholangiocarcinoma with or without previous resection of liver for hepatolithiasis

Joon Young Lee, Jae Seon Kim, Ji Mi Moon, Sang Ah Lim, Wonho Chung, Eun Hye Lim, Beomjae Lee, Jong Jae Park, Young-Tae Bak

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12 Citations (Scopus)

Abstract

Background/Aims: To investigate the incidence of cholangiocarcinoma in patients with hepatolithiasis with or without previous resection of liver. Methods: From 2002 to 2009, we retrospectively reviewed 117 patients who were diagnosed and treated for hepatolithiasis in Korea University Guro Hospital. Among the 117 patients, 55 patients who were lost during follow-up were excluded, and 62 patients were eligible for analysis. The hepatic resection group (n=25) included patients who underwent left hemihepatectomy (n=2); left lateral segmentectomy (n=10); left lobectomy (n=9); right lobectomy (n=3); or wedge resection (n=1). The nonhepatic resection group (n=37) included transhepatic cholangiographic lithotomy and endoscopic retrograde cholangiopancreatography-treated patients. The mean follow-up period was 47 months. Results: The incidence of cholangiocarcinoma while patients were followed for hepatolithiasis was 12.9% (8/62) (hepatic resection group, three cases [12%] vs nonhepatic resection group, five cases [13.5%]; p=1.000). The mean follow-up period was 53 months (47±11 months) until the diagnosis of cholangiocarcinoma. Conclusions: There was no difference in the incidence of cholangiocarcinoma according to previous liver resections. Patients with hepatolithiasis should be carefully followed up for detection of cholangiocarcinoma even after a previous liver resection.

Original languageEnglish
Pages (from-to)475-479
Number of pages5
JournalGut and Liver
Volume7
Issue number4
DOIs
Publication statusPublished - 2013 Jul 1

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Cholangiocarcinoma
Liver
Incidence
Segmental Mastectomy
Endoscopic Retrograde Cholangiopancreatography
Korea

Keywords

  • Cholangiocarcinoma
  • Hepatolithiasis
  • Liver resection

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Incidence of cholangiocarcinoma with or without previous resection of liver for hepatolithiasis. / Lee, Joon Young; Kim, Jae Seon; Moon, Ji Mi; Lim, Sang Ah; Chung, Wonho; Lim, Eun Hye; Lee, Beomjae; Park, Jong Jae; Bak, Young-Tae.

In: Gut and Liver, Vol. 7, No. 4, 01.07.2013, p. 475-479.

Research output: Contribution to journalArticle

Lee, Joon Young ; Kim, Jae Seon ; Moon, Ji Mi ; Lim, Sang Ah ; Chung, Wonho ; Lim, Eun Hye ; Lee, Beomjae ; Park, Jong Jae ; Bak, Young-Tae. / Incidence of cholangiocarcinoma with or without previous resection of liver for hepatolithiasis. In: Gut and Liver. 2013 ; Vol. 7, No. 4. pp. 475-479.
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