Abstract
Background Studies investigating the epidemiology and mortality of Takayasu Arteritis (TA) are scarce. The objective of this study was to provide information regarding the epidemiology of TA, such as the incidence, prevalence, survival and cause of death in Korea. Methods We used a national, population-based database maintained by the Rare Intractable Disease registration program and the Health Insurance Review and Assessment Service, which includes information on all TA patients, diagnosed based on uniform criteria. We also used data from Statistics Korea linked with RID database to confirm survival and cause of death. We analyzed data for the period 2008–2012. Results During study period, there were 612 new patients with TA, with a female-to-male ratio of 4.3:1. The annual mean incidence was 0.24 per 105 people, and the prevalence was 2.82 per 105 people in 2012. The average annual mortality rate was 0.02 per 105 people, and the standardized mortality ratio was 3.1 per 105 people. The overall survival of patients with TA was 96.6%, which was significantly lower than that in the general population. Cardiovascular disease was the most common cause of death, accounting for 29 of the 64 deaths (45.3%), followed by neoplasms in 9 patients (14.1%). Conclusions The incidence and prevalence presented in this study are the highest ever reported. The survival of patients with TA was significantly lower than that of the general population, and the main cause of death was cardiovascular disease. This study reflects the need for greater awareness of TA, especially in Asian countries.
| Original language | English |
|---|---|
| Pages (from-to) | 100-104 |
| Number of pages | 5 |
| Journal | International Journal of Cardiology |
| Volume | 235 |
| DOIs | |
| Publication status | Published - 2017 May 15 |
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Keywords
- Epidemiology
- Incidence
- Mortality
- Takayasu arteritis
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Incidence, prevalence, mortality and causes of death in Takayasu Arteritis in Korea – A nationwide, population-based study. / Park, Sang Jun; Kim, Hyun Jung; Park, Hojong; Hann, Hoo Jae; Kim, Kyoung Hoon; Han, Seungjin; Kim, Yuri; Ahn, Hyeong Sik.
In: International Journal of Cardiology, Vol. 235, 15.05.2017, p. 100-104.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Incidence, prevalence, mortality and causes of death in Takayasu Arteritis in Korea – A nationwide, population-based study
AU - Park, Sang Jun
AU - Kim, Hyun Jung
AU - Park, Hojong
AU - Hann, Hoo Jae
AU - Kim, Kyoung Hoon
AU - Han, Seungjin
AU - Kim, Yuri
AU - Ahn, Hyeong Sik
PY - 2017/5/15
Y1 - 2017/5/15
N2 - Background Studies investigating the epidemiology and mortality of Takayasu Arteritis (TA) are scarce. The objective of this study was to provide information regarding the epidemiology of TA, such as the incidence, prevalence, survival and cause of death in Korea. Methods We used a national, population-based database maintained by the Rare Intractable Disease registration program and the Health Insurance Review and Assessment Service, which includes information on all TA patients, diagnosed based on uniform criteria. We also used data from Statistics Korea linked with RID database to confirm survival and cause of death. We analyzed data for the period 2008–2012. Results During study period, there were 612 new patients with TA, with a female-to-male ratio of 4.3:1. The annual mean incidence was 0.24 per 105 people, and the prevalence was 2.82 per 105 people in 2012. The average annual mortality rate was 0.02 per 105 people, and the standardized mortality ratio was 3.1 per 105 people. The overall survival of patients with TA was 96.6%, which was significantly lower than that in the general population. Cardiovascular disease was the most common cause of death, accounting for 29 of the 64 deaths (45.3%), followed by neoplasms in 9 patients (14.1%). Conclusions The incidence and prevalence presented in this study are the highest ever reported. The survival of patients with TA was significantly lower than that of the general population, and the main cause of death was cardiovascular disease. This study reflects the need for greater awareness of TA, especially in Asian countries.
AB - Background Studies investigating the epidemiology and mortality of Takayasu Arteritis (TA) are scarce. The objective of this study was to provide information regarding the epidemiology of TA, such as the incidence, prevalence, survival and cause of death in Korea. Methods We used a national, population-based database maintained by the Rare Intractable Disease registration program and the Health Insurance Review and Assessment Service, which includes information on all TA patients, diagnosed based on uniform criteria. We also used data from Statistics Korea linked with RID database to confirm survival and cause of death. We analyzed data for the period 2008–2012. Results During study period, there were 612 new patients with TA, with a female-to-male ratio of 4.3:1. The annual mean incidence was 0.24 per 105 people, and the prevalence was 2.82 per 105 people in 2012. The average annual mortality rate was 0.02 per 105 people, and the standardized mortality ratio was 3.1 per 105 people. The overall survival of patients with TA was 96.6%, which was significantly lower than that in the general population. Cardiovascular disease was the most common cause of death, accounting for 29 of the 64 deaths (45.3%), followed by neoplasms in 9 patients (14.1%). Conclusions The incidence and prevalence presented in this study are the highest ever reported. The survival of patients with TA was significantly lower than that of the general population, and the main cause of death was cardiovascular disease. This study reflects the need for greater awareness of TA, especially in Asian countries.
KW - Epidemiology
KW - Incidence
KW - Mortality
KW - Takayasu arteritis
UR - http://www.scopus.com/inward/record.url?scp=85014517149&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85014517149&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2017.02.086
DO - 10.1016/j.ijcard.2017.02.086
M3 - Article
C2 - 28283361
AN - SCOPUS:85014517149
VL - 235
SP - 100
EP - 104
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -