Increase of olfactory threshold in plating factory workers exposed to chromium in Korea

Fumihiko Kitamura, Kazuhito Yokoyama, Shunichi Araki, Mariko Nishikitani, Jae Wook Choi, Youg Tae Yum, Hee Chan Park, Sang Hwoi Park, Hajime Sato

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Abstract

To disclose the effects of chromium (Cr) on olfactory function, olfactory threshold tests were conducted on 27 male plating workers (Cr workers) with signs and symptoms of olfactory irritation but without nasal septum perforation or ulcer and on 34 male control subjects in Korean plating factories. The Cr workers had been exposed to Cr fume for 0.9 to 18.2 (mean 7.9) years; their blood Cr concentrations (0.16-3.69, mean 1.29 μg/dl) were significantly higher than those of the 34 control subjects (0.04-1.95, mean 0.55 μg/dl). Scores on recognition thresholds among the Cr workers were significantly higher than those of the control subjects (p<0.05) and related positively and significantly to the exposure periods of the 27 Cr workers (p<0.05). Olfactory thresholds were not significantly different between the Cr workers with and without nasal signs or symptoms, except that the scores on the recognition threshold were significantly higher in those experiencing difficulty with smell (p<0.05). It is suggested that olfactory threshold is affected by Cr without development of nasal septum perforation or ulceration.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
JournalIndustrial Health
Volume41
Issue number3
DOIs
Publication statusPublished - 2003 Jan 1

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Keywords

  • Chromium
  • Nasal septum
  • Olfactometry
  • Olfactory threshold
  • Plating factory workers

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Kitamura, F., Yokoyama, K., Araki, S., Nishikitani, M., Choi, J. W., Yum, Y. T., Park, H. C., Park, S. H., & Sato, H. (2003). Increase of olfactory threshold in plating factory workers exposed to chromium in Korea. Industrial Health, 41(3), 279-285. https://doi.org/10.2486/indhealth.41.279