TY - JOUR
T1 - Indications of external radiotherapy for hepatocellular carcinoma from updated clinical guidelines
T2 - Diverse global viewpoints
AU - Park, Sunmin
AU - Yoon, Won Sup
AU - Rim, Chai Hong
N1 - Publisher Copyright:
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
PY - 2020/1/28
Y1 - 2020/1/28
N2 - The etiology and disease patterns of hepatocellular carcinoma (HCC) significantly vary among regions. Modern standard treatments commonly require multidisciplinary approaches, including applications of up-to date medicine and advanced procedures, and necessitate the support of socioeconomic systems. For these reasons, a number of clinical guidelines for HCC from different associations and regions have been presented. External beam radiation therapy was contraindicated for HCC until a few decades ago, but with the development of new technologies, its application has rapidly increased as selective irradiation for tumorous lesions became possible. Most of the guidelines had been opposed or indifferent to radiotherapy in the past, but several guidelines have introduced indications and recommendations for radiotherapy in their updated versions. This review will discuss the characteristics of important guidelines and their contents regarding radiotherapy and will also provide guidance to physicians who are considering applications of locoregional modalities that include radiotherapy.
AB - The etiology and disease patterns of hepatocellular carcinoma (HCC) significantly vary among regions. Modern standard treatments commonly require multidisciplinary approaches, including applications of up-to date medicine and advanced procedures, and necessitate the support of socioeconomic systems. For these reasons, a number of clinical guidelines for HCC from different associations and regions have been presented. External beam radiation therapy was contraindicated for HCC until a few decades ago, but with the development of new technologies, its application has rapidly increased as selective irradiation for tumorous lesions became possible. Most of the guidelines had been opposed or indifferent to radiotherapy in the past, but several guidelines have introduced indications and recommendations for radiotherapy in their updated versions. This review will discuss the characteristics of important guidelines and their contents regarding radiotherapy and will also provide guidance to physicians who are considering applications of locoregional modalities that include radiotherapy.
KW - Clinical guideline
KW - Hepatocellular carcinoma
KW - Liver neoplasm
KW - Radiation therapy
KW - Radiotherapy
KW - Stereotactic body radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=85079586011&partnerID=8YFLogxK
U2 - 10.3748/wjg.v26.i4.393
DO - 10.3748/wjg.v26.i4.393
M3 - Review article
C2 - 32063688
AN - SCOPUS:85079586011
VL - 26
SP - 393
EP - 403
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 8
ER -