Abstract
Restless legs syndrome (RLS) is a sensorimotor neurological disturbance causing physical and psychological distress. Here, we investigated the severity and effect of depressive symptoms in RLS among a Korean cohort population. Depressive symptoms were more prevalent in the RLS group than in the non-RLS group [≥mild depression: odds ratio (OR)=1.95, p<0.001; ≥ moderate depression: OR=6.15, p<0.001; and ≥severe depression: OR=56.54, p<0.001], with a predominant proportion of severe depression (97%) in the RLS group. We found that difficulty falling asleep (OR=8.16, p<0.001), broken sleep (OR=11.66, p=0.001), early morning awakening (OR=8.5, p<0.001), and excessive daytime sleepiness (OR=3.04, p=0.031) were significantly frequent in individuals with severe depression in the RLS group. Red blood cell count was significantly low in individuals with severe depression in the RLS group (p=0.041). We found that severe depression was associated with RLS, suggesting the evaluation and management of mood symptoms and sleep-related and hematological features when treating RLS.
Original language | English |
---|---|
Pages (from-to) | 887-893 |
Number of pages | 7 |
Journal | Psychiatry Investigation |
Volume | 14 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2017 Nov |
Keywords
- Daytime sleepiness
- Depressive symptom
- Hematological features
- Insomnia
- Restless legs syndrome
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry