Abstract
Restless legs syndrome (RLS) is a sensorimotor neurological disturbance causing physical and psychological distress. Here, we investigated the severity and effect of depressive symptoms in RLS among a Korean cohort population. Depressive symptoms were more prevalent in the RLS group than in the non-RLS group [≥mild depression: odds ratio (OR)=1.95, p<0.001; ≥ moderate depression: OR=6.15, p<0.001; and ≥severe depression: OR=56.54, p<0.001], with a predominant proportion of severe depression (97%) in the RLS group. We found that difficulty falling asleep (OR=8.16, p<0.001), broken sleep (OR=11.66, p=0.001), early morning awakening (OR=8.5, p<0.001), and excessive daytime sleepiness (OR=3.04, p=0.031) were significantly frequent in individuals with severe depression in the RLS group. Red blood cell count was significantly low in individuals with severe depression in the RLS group (p=0.041). We found that severe depression was associated with RLS, suggesting the evaluation and management of mood symptoms and sleep-related and hematological features when treating RLS.
| Original language | English |
|---|---|
| Pages (from-to) | 887-893 |
| Number of pages | 7 |
| Journal | Psychiatry Investigation |
| Volume | 14 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2017 Nov 1 |
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Keywords
- Daytime sleepiness
- Depressive symptom
- Hematological features
- Insomnia
- Restless legs syndrome
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
Cite this
Individuals with restless legs syndrome tend to have severe depressive symptoms : Findings from a community-based cohort study. / Cho, Chul Hyun; Kim, Leen; Lee, Heon-Jeong.
In: Psychiatry Investigation, Vol. 14, No. 6, 01.11.2017, p. 887-893.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Individuals with restless legs syndrome tend to have severe depressive symptoms
T2 - Findings from a community-based cohort study
AU - Cho, Chul Hyun
AU - Kim, Leen
AU - Lee, Heon-Jeong
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Restless legs syndrome (RLS) is a sensorimotor neurological disturbance causing physical and psychological distress. Here, we investigated the severity and effect of depressive symptoms in RLS among a Korean cohort population. Depressive symptoms were more prevalent in the RLS group than in the non-RLS group [≥mild depression: odds ratio (OR)=1.95, p<0.001; ≥ moderate depression: OR=6.15, p<0.001; and ≥severe depression: OR=56.54, p<0.001], with a predominant proportion of severe depression (97%) in the RLS group. We found that difficulty falling asleep (OR=8.16, p<0.001), broken sleep (OR=11.66, p=0.001), early morning awakening (OR=8.5, p<0.001), and excessive daytime sleepiness (OR=3.04, p=0.031) were significantly frequent in individuals with severe depression in the RLS group. Red blood cell count was significantly low in individuals with severe depression in the RLS group (p=0.041). We found that severe depression was associated with RLS, suggesting the evaluation and management of mood symptoms and sleep-related and hematological features when treating RLS.
AB - Restless legs syndrome (RLS) is a sensorimotor neurological disturbance causing physical and psychological distress. Here, we investigated the severity and effect of depressive symptoms in RLS among a Korean cohort population. Depressive symptoms were more prevalent in the RLS group than in the non-RLS group [≥mild depression: odds ratio (OR)=1.95, p<0.001; ≥ moderate depression: OR=6.15, p<0.001; and ≥severe depression: OR=56.54, p<0.001], with a predominant proportion of severe depression (97%) in the RLS group. We found that difficulty falling asleep (OR=8.16, p<0.001), broken sleep (OR=11.66, p=0.001), early morning awakening (OR=8.5, p<0.001), and excessive daytime sleepiness (OR=3.04, p=0.031) were significantly frequent in individuals with severe depression in the RLS group. Red blood cell count was significantly low in individuals with severe depression in the RLS group (p=0.041). We found that severe depression was associated with RLS, suggesting the evaluation and management of mood symptoms and sleep-related and hematological features when treating RLS.
KW - Daytime sleepiness
KW - Depressive symptom
KW - Hematological features
KW - Insomnia
KW - Restless legs syndrome
UR - http://www.scopus.com/inward/record.url?scp=85034251699&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85034251699&partnerID=8YFLogxK
U2 - 10.4306/pi.2017.14.6.887
DO - 10.4306/pi.2017.14.6.887
M3 - Article
AN - SCOPUS:85034251699
VL - 14
SP - 887
EP - 893
JO - Psychiatry Investigation
JF - Psychiatry Investigation
SN - 1738-3684
IS - 6
ER -