Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces

Ji-Hun Seo, Sachiro Kakinoki, Yuuki Inoue, Tetsuji Yamaoka, Kazuhiko Ishihara, Nobuhiko Yui

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

The rapid response of integrin β1 molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material-cell interactions.

Original languageEnglish
Pages (from-to)5513-5516
Number of pages4
JournalJournal of the American Chemical Society
Volume135
Issue number15
DOIs
Publication statusPublished - 2013 Apr 17
Externally publishedYes

Fingerprint

Integrins
Peptides
Molecules
Cyclodextrins
Cell Communication
Cell Membrane
Cell membranes
arginyl-glycyl-aspartic acid
polyrotaxane

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces. / Seo, Ji-Hun; Kakinoki, Sachiro; Inoue, Yuuki; Yamaoka, Tetsuji; Ishihara, Kazuhiko; Yui, Nobuhiko.

In: Journal of the American Chemical Society, Vol. 135, No. 15, 17.04.2013, p. 5513-5516.

Research output: Contribution to journalArticle

Seo, Ji-Hun ; Kakinoki, Sachiro ; Inoue, Yuuki ; Yamaoka, Tetsuji ; Ishihara, Kazuhiko ; Yui, Nobuhiko. / Inducing rapid cellular response on RGD-binding threaded macromolecular surfaces. In: Journal of the American Chemical Society. 2013 ; Vol. 135, No. 15. pp. 5513-5516.
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