Industrial production of fructooligosaccharides by immobilized cells of Aureobasidium pullulans in a packed bed reactor

K. H. Jung, S. H. Bang, T. K. Oh, H. J. Park

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Continuous production of fructooligosaccharides (FOS) by Aureobasidium pullulans immobilized on calcium alginate beads with a packed bed was investigated at a plant scale reactor. Optimum conditions were with 770 g sucrose/l, being fed at 200 l/h at 50°C which gave a productivity of 180 g FOS/l h. Initial activity was maintained for more than 100 days. The reactor was successfully scaled up to a production scale of 1. 2 m 3.

Original languageEnglish
Pages (from-to)1621-1624
Number of pages4
JournalBiotechnology letters
Volume33
Issue number8
DOIs
Publication statusPublished - 2011 Aug

Keywords

  • Cell immobilization
  • Fructooligosaccharides
  • Fructosyltransferase
  • Packed bed reactor

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

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