Infection rate of Leptospira interrogans in the field rodent, Apodemus agrarius, in Korea

M. K. Cho, Sun-Ho Kee, H. J. Song, K. H. Kim, Ki-Joon Song, L. J. Baek, H. H. Kim, H. B. Oh, Y. W. Kim, W. H. Chang

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Abstract

Leptospirosis has significantly decreased in Korea since 1988, following the leptospiral vaccination programme initiated in 1988. Whether this wholly explains the decreased incidence is uncertain. As an initial step to answer this question, infection rates of Leptospira interrogans in field rodents, Apodemis agrarius, were examined and compared with previous data. Two hundred and twenty-two A. agrarius were captured during October-December 1996. Spirochaetes were isolated from 22 (9.9%) and leptospiral DNA was detected in an additional 6 rodents (12.6%). Subsequent microscopic agglutination tests (MAT) classified all these isolates as L. interrogans serogroup Icterohaemorrhagiae serovar lai. The above data did not significantly differ from previous surveys in 1984-7. There was no significant change of L. interrogans infection in field rodents following the introduction of the vaccination programme in Korea. Further studies are needed to determine the role of human vaccination in reducing incidence.

Original languageEnglish
Pages (from-to)685-690
Number of pages6
JournalEpidemiology and Infection
Volume121
Issue number3
DOIs
Publication statusPublished - 1998 Dec 1

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Leptospira interrogans
Murinae
Korea
Rodentia
Vaccination
Leptospira interrogans serovar icterohaemorrhagiae
Infection
Spirochaetales
Agglutination Tests
Leptospirosis
Incidence
DNA

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

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Infection rate of Leptospira interrogans in the field rodent, Apodemus agrarius, in Korea. / Cho, M. K.; Kee, Sun-Ho; Song, H. J.; Kim, K. H.; Song, Ki-Joon; Baek, L. J.; Kim, H. H.; Oh, H. B.; Kim, Y. W.; Chang, W. H.

In: Epidemiology and Infection, Vol. 121, No. 3, 01.12.1998, p. 685-690.

Research output: Contribution to journalArticle

Cho, M. K. ; Kee, Sun-Ho ; Song, H. J. ; Kim, K. H. ; Song, Ki-Joon ; Baek, L. J. ; Kim, H. H. ; Oh, H. B. ; Kim, Y. W. ; Chang, W. H. / Infection rate of Leptospira interrogans in the field rodent, Apodemus agrarius, in Korea. In: Epidemiology and Infection. 1998 ; Vol. 121, No. 3. pp. 685-690.
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