Inflammatory myofibroblastic tumor of the larynx

Sang Il Suh, Hae Young Seol, Jean Hwa Lee, Young Hen Lee, Taik Kun Kim, Nam Joon Lee, Jeong Soo Woo, In Sun Kim

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24 Citations (Scopus)

Abstract

Background. Inflammatory myofibroblastic tumor, composed of myofibroblastic spindle cells with acute and chronic inflammatory cells, is an unusual, benign solid mass that mimics a neoplastic process. Methods. We report a rare case of a patient with a laryngeal inflammatory myofibroblastic tumor. Laryngoscopy demonstrated a submucosal mass involving the right false cord. The mass was a well-enhanced supraglottic lesion on CT scan. It showed medially high signal intensity and peripherally low signal intensity on T2-weighted MR images, and it displayed a high magnetization transfer ratio; before surgery, it was believed to be a malignant tumor. Laryngoscopic biopsy was performed. Pathologic features of the specimen were diagnostic for inflammatory myofibroblastic tumor. Results. Steroid therapy was chosen for further treatment. No recurrence was observed for 4 years. Conclusion. In patients with chronic hoarseness who have a malignant-looking submucosal laryngeal mass, inflammatory myofibroblastic tumor should be considered. Conservative surgery and steroid treatment are advocated because of laryngeal preservation.

Original languageEnglish
Pages (from-to)369-372
Number of pages4
JournalHead and Neck
Volume28
Issue number4
DOIs
Publication statusPublished - 2006 Apr

Keywords

  • CT imaging
  • Inflammatory myofibroblastic tumor
  • Larynx
  • MR imaging
  • Steroid therapy

ASJC Scopus subject areas

  • Otorhinolaryngology

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  • Cite this

    Suh, S. I., Seol, H. Y., Lee, J. H., Lee, Y. H., Kim, T. K., Lee, N. J., Woo, J. S., & Kim, I. S. (2006). Inflammatory myofibroblastic tumor of the larynx. Head and Neck, 28(4), 369-372. https://doi.org/10.1002/hed.20413