Inflammatory myofibroblastic tumor of the larynx

Sang Il Suh, Hae Young Seol, Jean Hwa Lee, Young Hen Lee, Taik Kun Kim, Nam Joon Lee, Jeong Soo Woo, In Sun Kim

    Research output: Contribution to journalArticlepeer-review

    24 Citations (Scopus)

    Abstract

    Background. Inflammatory myofibroblastic tumor, composed of myofibroblastic spindle cells with acute and chronic inflammatory cells, is an unusual, benign solid mass that mimics a neoplastic process. Methods. We report a rare case of a patient with a laryngeal inflammatory myofibroblastic tumor. Laryngoscopy demonstrated a submucosal mass involving the right false cord. The mass was a well-enhanced supraglottic lesion on CT scan. It showed medially high signal intensity and peripherally low signal intensity on T2-weighted MR images, and it displayed a high magnetization transfer ratio; before surgery, it was believed to be a malignant tumor. Laryngoscopic biopsy was performed. Pathologic features of the specimen were diagnostic for inflammatory myofibroblastic tumor. Results. Steroid therapy was chosen for further treatment. No recurrence was observed for 4 years. Conclusion. In patients with chronic hoarseness who have a malignant-looking submucosal laryngeal mass, inflammatory myofibroblastic tumor should be considered. Conservative surgery and steroid treatment are advocated because of laryngeal preservation.

    Original languageEnglish
    Pages (from-to)369-372
    Number of pages4
    JournalHead and Neck
    Volume28
    Issue number4
    DOIs
    Publication statusPublished - 2006 Apr

    Keywords

    • CT imaging
    • Inflammatory myofibroblastic tumor
    • Larynx
    • MR imaging
    • Steroid therapy

    ASJC Scopus subject areas

    • Otorhinolaryngology

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