Influence of chitosan coating on the liposomal surface on physicochemical properties and the release profile of nanocarrier systems

S. H. Bang, I. C. Hwang, Y. M. Yu, H. R. Kwon, D. H. Kim, Hyun Jin Park

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Chitosan-coated nanoliposomes containing etofenprox or alpha-cypermethrin prepared by ultrasonic homogenization maintained a size distribution in the nanometre range. Nanoliposomes were constructed using different types and concentrations of chitosan to regulate the mean size and surface charge. As the chitosan concentration (0.10.5%, w/v) and the degree of deacetylation increased, surface charge also increased. The encapsulation efficiency and release profile were measured by gas chromatography. Encapsulation efficiency decreased slightly as chitosan concentration increased (0.10.5%, w/v). As the intrinsic surface charge or concentration of the coating material increased, the release period of the entrapped core material was extended (chitosans A and B; 0.1 and 0.3%, w/v). The results indicate that diverse preparation conditions could affect the physicochemical properties and release profile of the resulting nanocarrier systems.

Original languageEnglish
Pages (from-to)595-604
Number of pages10
JournalJournal of Microencapsulation
Volume28
Issue number7
DOIs
Publication statusPublished - 2011 Nov 1

Fingerprint

Chitosan
coatings
Coatings
Surface charge
profiles
Encapsulation
gas chromatography
homogenizing
Ultrasonics
ultrasonics
Gas chromatography
Gas Chromatography
preparation

Keywords

  • Chitosan
  • Chitosan-coated liposome
  • Controlled release
  • Nanocarrier system
  • Phosphatidylcholine
  • Self-assembly

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry
  • Bioengineering
  • Organic Chemistry

Cite this

Influence of chitosan coating on the liposomal surface on physicochemical properties and the release profile of nanocarrier systems. / Bang, S. H.; Hwang, I. C.; Yu, Y. M.; Kwon, H. R.; Kim, D. H.; Park, Hyun Jin.

In: Journal of Microencapsulation, Vol. 28, No. 7, 01.11.2011, p. 595-604.

Research output: Contribution to journalArticle

@article{efa0f3893958455082b3bb2ab4294fee,
title = "Influence of chitosan coating on the liposomal surface on physicochemical properties and the release profile of nanocarrier systems",
abstract = "Chitosan-coated nanoliposomes containing etofenprox or alpha-cypermethrin prepared by ultrasonic homogenization maintained a size distribution in the nanometre range. Nanoliposomes were constructed using different types and concentrations of chitosan to regulate the mean size and surface charge. As the chitosan concentration (0.10.5{\%}, w/v) and the degree of deacetylation increased, surface charge also increased. The encapsulation efficiency and release profile were measured by gas chromatography. Encapsulation efficiency decreased slightly as chitosan concentration increased (0.10.5{\%}, w/v). As the intrinsic surface charge or concentration of the coating material increased, the release period of the entrapped core material was extended (chitosans A and B; 0.1 and 0.3{\%}, w/v). The results indicate that diverse preparation conditions could affect the physicochemical properties and release profile of the resulting nanocarrier systems.",
keywords = "Chitosan, Chitosan-coated liposome, Controlled release, Nanocarrier system, Phosphatidylcholine, Self-assembly",
author = "Bang, {S. H.} and Hwang, {I. C.} and Yu, {Y. M.} and Kwon, {H. R.} and Kim, {D. H.} and Park, {Hyun Jin}",
year = "2011",
month = "11",
day = "1",
doi = "10.3109/02652048.2011.557748",
language = "English",
volume = "28",
pages = "595--604",
journal = "Journal of Microencapsulation",
issn = "0265-2048",
publisher = "Informa Healthcare",
number = "7",

}

TY - JOUR

T1 - Influence of chitosan coating on the liposomal surface on physicochemical properties and the release profile of nanocarrier systems

AU - Bang, S. H.

AU - Hwang, I. C.

AU - Yu, Y. M.

AU - Kwon, H. R.

AU - Kim, D. H.

AU - Park, Hyun Jin

PY - 2011/11/1

Y1 - 2011/11/1

N2 - Chitosan-coated nanoliposomes containing etofenprox or alpha-cypermethrin prepared by ultrasonic homogenization maintained a size distribution in the nanometre range. Nanoliposomes were constructed using different types and concentrations of chitosan to regulate the mean size and surface charge. As the chitosan concentration (0.10.5%, w/v) and the degree of deacetylation increased, surface charge also increased. The encapsulation efficiency and release profile were measured by gas chromatography. Encapsulation efficiency decreased slightly as chitosan concentration increased (0.10.5%, w/v). As the intrinsic surface charge or concentration of the coating material increased, the release period of the entrapped core material was extended (chitosans A and B; 0.1 and 0.3%, w/v). The results indicate that diverse preparation conditions could affect the physicochemical properties and release profile of the resulting nanocarrier systems.

AB - Chitosan-coated nanoliposomes containing etofenprox or alpha-cypermethrin prepared by ultrasonic homogenization maintained a size distribution in the nanometre range. Nanoliposomes were constructed using different types and concentrations of chitosan to regulate the mean size and surface charge. As the chitosan concentration (0.10.5%, w/v) and the degree of deacetylation increased, surface charge also increased. The encapsulation efficiency and release profile were measured by gas chromatography. Encapsulation efficiency decreased slightly as chitosan concentration increased (0.10.5%, w/v). As the intrinsic surface charge or concentration of the coating material increased, the release period of the entrapped core material was extended (chitosans A and B; 0.1 and 0.3%, w/v). The results indicate that diverse preparation conditions could affect the physicochemical properties and release profile of the resulting nanocarrier systems.

KW - Chitosan

KW - Chitosan-coated liposome

KW - Controlled release

KW - Nanocarrier system

KW - Phosphatidylcholine

KW - Self-assembly

UR - http://www.scopus.com/inward/record.url?scp=80053410902&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053410902&partnerID=8YFLogxK

U2 - 10.3109/02652048.2011.557748

DO - 10.3109/02652048.2011.557748

M3 - Article

C2 - 21861589

AN - SCOPUS:80053410902

VL - 28

SP - 595

EP - 604

JO - Journal of Microencapsulation

JF - Journal of Microencapsulation

SN - 0265-2048

IS - 7

ER -