Influenza vaccines: Unmet needs and recent developments

Ji Yun Noh, Woo Joo Kim

    Research output: Contribution to journalReview articlepeer-review

    18 Citations (Scopus)

    Abstract

    Influenza is a worldwide public health concern. Since the introduction of trivalent influenza vaccine in 1978, vaccination has been the primary means of prevention and control of influenza. Current influenza vaccines have moderate efficacy, good safety, and acceptable tolerability; however, they have unsatisfactory efficacy in older adults, are dependent on egg supply for production, and are time-consuming to manufacture. This review outlines the unmet medical needs of current influenza vaccines. Recent developments in influenza vaccines are also described.

    Original languageEnglish
    Pages (from-to)375-386
    Number of pages12
    JournalInfection and Chemotherapy
    Volume45
    Issue number4
    DOIs
    Publication statusPublished - 2013 Dec

    Keywords

    • Human
    • Influenza
    • Influenza vaccines
    • Pandemics

    ASJC Scopus subject areas

    • Infectious Diseases
    • Pharmacology (medical)

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