Initial experience of magnetic resonance imaging/ ultrasonography fusion transperineal biopsy: Biopsy techniques and results for 75 patients

Jong Hyun Tae, Ji Sung Shim, Hyun Jung Jin, Sung Goo Yoon, Tae Il No, Jae Yoon Kim, Seok Ho Kang, Jun Cheon, Sung-Gu Kang

Research output: Contribution to journalArticle


Purpose: The aim of this study is to describe the technique and to report early results of transperineal magnetic resonance imaging and ultrasonography (MRI-US) fusion biopsy. Materials and Methods: A total of 75 patients underwent MRI-US fusion transperineal biopsy. Targeted biopsy via MRI-US fusion imaging was carried out for cancer-suspicious lesions with additional systematic biopsy. Detection rates for overall and clinically significant prostate cancer (csPCa) were evaluated and compared between systematic and targeted biopsy. In addition, further investigation into the detection rate according to prostate imaging reporting and data system (PI-RADS) score was done. Results of repeat biopsies were also evaluated. Results: Overall cancer detection rate was 61.3% (46 patients) and the detection rate for csPCa was 42.7% (32 patients). Overall detection rates for systematic and targeted biopsy were 41.3% and 57.3% (p<0.05), respectively. Detection rates for csPCa were 26.7% and 41.3%, respectively (p<0.05). The cancer detection rates via MRI fusion target biopsy were 30.8% in PI-RADS 3, 62.1% in PI-RADS 4 and 89.4% in PI-RADS 5. Rates of csPCa missed by targeted biopsy and systematic biopsy were 0.0% and 25.0%, respectively. The cancer detection rate in repeat biopsies was 61.1% (11 among 18 patients) in which 55.5% of cancer suspected lesions were located in the anterior portion. Conclusions: Transperineal MRI-US fusion biopsy is useful for improving overall cancer detection rate and especially detection of csPCa. Transperineal MRI-US targeted biopsy show potential benefits to improve cancer detection rate in patients with high PI-RADS score, tumor located at the anterior portion and in repeat biopsies.

Original languageEnglish
Pages (from-to)363-370
Number of pages8
JournalInvestigative and Clinical Urology
Issue number6
Publication statusPublished - 2018 Jan 1



  • Biopsy
  • Magnetic resonance imaging
  • Prostatic neoplasms
  • Ultrasonography

ASJC Scopus subject areas

  • Urology

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