Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients

Jong Su Park, Su Jin Kim, Sung Woo Lee, Eui Jung Lee, Kap Su Han, Sungwoo Moon, Yun Sik Hong

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background In severe sepsis and septic shock, global tissue hypoxia is a key development preceding multi-organ failure and death. Objective Our aim was to find whether the initial low oxygen extraction ratio (OER) is related to the severity of organ dysfunction and to predict the in-hospital mortality in severe sepsis or septic shock patients. Methods This was a secondary analysis of 169 patients with severe sepsis or septic shock in an emergency department. We calculated OER with 1- central venous oxygen saturation (ScvO2)/arterial oxygen saturation and compared the data according to the level of OER (high > 0.3, 0.2).

Original languageEnglish
Pages (from-to)261-267
Number of pages7
JournalJournal of Emergency Medicine
Volume49
Issue number3
DOIs
Publication statusPublished - 2015 Sep 1

Keywords

  • central venous oxygen saturation
  • mortality
  • organ dysfunction
  • oxygen extraction ratio
  • sepsis

ASJC Scopus subject areas

  • Emergency Medicine

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