Initial Low Oxygen Extraction Ratio Is Related to Severe Organ Dysfunction and High In-Hospital Mortality in Severe Sepsis and Septic Shock Patients

Jong Su Park, Su Jin Kim, Sung Woo Lee, Eui Jung Lee, Kap Su Han, Sung Woo Moon, Yun Sik Hong

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)

    Abstract

    Background In severe sepsis and septic shock, global tissue hypoxia is a key development preceding multi-organ failure and death. Objective Our aim was to find whether the initial low oxygen extraction ratio (OER) is related to the severity of organ dysfunction and to predict the in-hospital mortality in severe sepsis or septic shock patients. Methods This was a secondary analysis of 169 patients with severe sepsis or septic shock in an emergency department. We calculated OER with 1- central venous oxygen saturation (ScvO2)/arterial oxygen saturation and compared the data according to the level of OER (high > 0.3, 0.2).

    Original languageEnglish
    Pages (from-to)261-267
    Number of pages7
    JournalJournal of Emergency Medicine
    Volume49
    Issue number3
    DOIs
    Publication statusPublished - 2015 Sep 1

    Keywords

    • central venous oxygen saturation
    • mortality
    • organ dysfunction
    • oxygen extraction ratio
    • sepsis

    ASJC Scopus subject areas

    • Emergency Medicine

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