TY - JOUR
T1 - Injectable tissue-engineered soft tissue for tissue augmentation
AU - Rhee, Sung Mi
AU - You, Hi Jin
AU - Han, Seung Kyu
PY - 2014
Y1 - 2014
N2 - Soft tissue augmentation is a process of implanting tissues or materials to treat wrinkles or soft tissue defects in the body. Over the years, various materials have evolved to correct soft tissue defects, including a number of tissues and polymers. Autogenous dermis, autogenous fat, autogenous dermis-fat, allogenic dermis, synthetic implants, and fillers have been widely accepted for soft tissue augmentations. Tissue engineering technology has also been introduced and opened a new venue of opportunities in this field. In particular, a long-lasting filler consisting of hyaluronic acid filler and living human mesenchymal cells called "injectable tissue-engineered soft tissue" has been created and applied clinically, as this strategy has many advantages over conventional methods. Fibroblasts and adipose-derived stromal vascular fraction cells can be clinically used as injectable tissue-engineered soft tissue at present. In this review, information on the soft tissue augmentation method using the injectable tissue-engineered soft tissue is provided.
AB - Soft tissue augmentation is a process of implanting tissues or materials to treat wrinkles or soft tissue defects in the body. Over the years, various materials have evolved to correct soft tissue defects, including a number of tissues and polymers. Autogenous dermis, autogenous fat, autogenous dermis-fat, allogenic dermis, synthetic implants, and fillers have been widely accepted for soft tissue augmentations. Tissue engineering technology has also been introduced and opened a new venue of opportunities in this field. In particular, a long-lasting filler consisting of hyaluronic acid filler and living human mesenchymal cells called "injectable tissue-engineered soft tissue" has been created and applied clinically, as this strategy has many advantages over conventional methods. Fibroblasts and adipose-derived stromal vascular fraction cells can be clinically used as injectable tissue-engineered soft tissue at present. In this review, information on the soft tissue augmentation method using the injectable tissue-engineered soft tissue is provided.
KW - Cell therapy
KW - Soft tissue
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84952665146&partnerID=8YFLogxK
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U2 - 10.3346/jkms.2014.29.S3.S170
DO - 10.3346/jkms.2014.29.S3.S170
M3 - Review article
C2 - 25473206
AN - SCOPUS:84952665146
VL - 29
SP - S170-S175
JO - Journal of Korean Medical Science
JF - Journal of Korean Medical Science
SN - 1011-8934
ER -