Integrated Biomarker Responses in Livers of the Pale Chub Zacco platypus for Risk Assessment of a Stream Contaminated by Wastewater Effluents

Palas Samanta, Hyungjoon Im, Joorim Na, Jinho Jung

Research output: Contribution to journalArticle

Abstract

We evaluated the effects of wastewater effluents on pale chub (Zacco platypus) in a contaminated stream by integrating genotoxic, oxidative stress, histological, and physiological biomarkers. The metal pollution index indicated higher pollution loads at downstream sites (DS1 and DS2) compared with the upstream reference site. Significantly higher nuclear abnormality confirmed the existence of genotoxicity (p < 0.05) at downstream sites. Antioxidant activity (catalase and glutathione S-transferase) and lipid peroxidation levels in livers of Z. platypus were also significantly higher at the DS1 site (p < 0.05). The liver somatic index was also influenced, with abnormal histological alterations in the liver, possibly caused by heavy metal accumulation (Cd, Co, Cr, Mn, Ni, and Pb). The integrated biomarker response value was the highest at DS1 (13.74) followed by DS2 (1.94), indicating that wastewater effluents had the potential to cause adverse effects on Z. platypus inhabiting receiving stream.

Original languageEnglish
JournalBulletin of Environmental Contamination and Toxicology
DOIs
Publication statusAccepted/In press - 2018 Jan 1

Fingerprint

Platypus
Cyprinidae
Biomarkers
Waste Water
Liver
Risk assessment
Effluents
Wastewater
Pollution
Oxidative stress
Heavy Metals
Glutathione Transferase
Antioxidants
Catalase
Lipids
Lipid Peroxidation
Heavy metals
DNA Damage
Oxidative Stress
Metals

Keywords

  • Biomarker
  • Effluent
  • Fish
  • Histology
  • Metal
  • Oxidative stress

ASJC Scopus subject areas

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

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title = "Integrated Biomarker Responses in Livers of the Pale Chub Zacco platypus for Risk Assessment of a Stream Contaminated by Wastewater Effluents",
abstract = "We evaluated the effects of wastewater effluents on pale chub (Zacco platypus) in a contaminated stream by integrating genotoxic, oxidative stress, histological, and physiological biomarkers. The metal pollution index indicated higher pollution loads at downstream sites (DS1 and DS2) compared with the upstream reference site. Significantly higher nuclear abnormality confirmed the existence of genotoxicity (p < 0.05) at downstream sites. Antioxidant activity (catalase and glutathione S-transferase) and lipid peroxidation levels in livers of Z. platypus were also significantly higher at the DS1 site (p < 0.05). The liver somatic index was also influenced, with abnormal histological alterations in the liver, possibly caused by heavy metal accumulation (Cd, Co, Cr, Mn, Ni, and Pb). The integrated biomarker response value was the highest at DS1 (13.74) followed by DS2 (1.94), indicating that wastewater effluents had the potential to cause adverse effects on Z. platypus inhabiting receiving stream.",
keywords = "Biomarker, Effluent, Fish, Histology, Metal, Oxidative stress",
author = "Palas Samanta and Hyungjoon Im and Joorim Na and Jinho Jung",
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T1 - Integrated Biomarker Responses in Livers of the Pale Chub Zacco platypus for Risk Assessment of a Stream Contaminated by Wastewater Effluents

AU - Samanta, Palas

AU - Im, Hyungjoon

AU - Na, Joorim

AU - Jung, Jinho

PY - 2018/1/1

Y1 - 2018/1/1

N2 - We evaluated the effects of wastewater effluents on pale chub (Zacco platypus) in a contaminated stream by integrating genotoxic, oxidative stress, histological, and physiological biomarkers. The metal pollution index indicated higher pollution loads at downstream sites (DS1 and DS2) compared with the upstream reference site. Significantly higher nuclear abnormality confirmed the existence of genotoxicity (p < 0.05) at downstream sites. Antioxidant activity (catalase and glutathione S-transferase) and lipid peroxidation levels in livers of Z. platypus were also significantly higher at the DS1 site (p < 0.05). The liver somatic index was also influenced, with abnormal histological alterations in the liver, possibly caused by heavy metal accumulation (Cd, Co, Cr, Mn, Ni, and Pb). The integrated biomarker response value was the highest at DS1 (13.74) followed by DS2 (1.94), indicating that wastewater effluents had the potential to cause adverse effects on Z. platypus inhabiting receiving stream.

AB - We evaluated the effects of wastewater effluents on pale chub (Zacco platypus) in a contaminated stream by integrating genotoxic, oxidative stress, histological, and physiological biomarkers. The metal pollution index indicated higher pollution loads at downstream sites (DS1 and DS2) compared with the upstream reference site. Significantly higher nuclear abnormality confirmed the existence of genotoxicity (p < 0.05) at downstream sites. Antioxidant activity (catalase and glutathione S-transferase) and lipid peroxidation levels in livers of Z. platypus were also significantly higher at the DS1 site (p < 0.05). The liver somatic index was also influenced, with abnormal histological alterations in the liver, possibly caused by heavy metal accumulation (Cd, Co, Cr, Mn, Ni, and Pb). The integrated biomarker response value was the highest at DS1 (13.74) followed by DS2 (1.94), indicating that wastewater effluents had the potential to cause adverse effects on Z. platypus inhabiting receiving stream.

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KW - Oxidative stress

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