Integrated run-to-run and on-line model-based control of particle size distribution for a semi-batch precipitation reactor

Kangwook Lee, Jay H. Lee, Dae Ryook Yang, Alan W. Mahoney

Research output: Contribution to journalArticle

38 Citations (Scopus)


The dynamics of particle size distribution (PSD) in a precipitation process are represented by a population balance (PB) and related differential-algebraic equations. The control of PSD is studied by using a closed-form solution of the PB. Batch-to-batch control and on-line single batch control strategies are investigated for controlling a semi-batch reactor. A systematic integration of the two strategies is shown to have a complementary effect on the control performance.

Original languageEnglish
Pages (from-to)1117-1131
Number of pages15
JournalComputers and Chemical Engineering
Issue number7-8
Publication statusPublished - 2002 Aug 15



  • Batch-to-batch
  • Extended Kalman filter
  • Least-squares
  • Model predictive control
  • Precipitation
  • Semi-batch

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Control and Systems Engineering

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