Abstract
We propose in this paper a new, simple, and cost-effective approach to two tasks: first, the fabrication of a co-enzyme-immobilized mass of single-walled carbon nanotubes (SWNTs) that has a specific microscale shape; second, the integration of the mass into a poly(dimethylsiloxane) (PDMS)-based microfluidic channel. An 80-μm-thick horseshoe-shaped SWNT microblock that had been physically immobilized with glucose oxidase (GOx) and horseradish peroxidase (HRP) was fabricated through the use of a 150-μm-thick flexible PDMS mold. The fabricated SWNT microblock was incorporated into the microfluidic channel for the bio-reaction on a microscale. This microfluidic device was tested for the spectroscopic glucose-detection, and the results showed that the glucose can be detected linearly (in log scale) in a wide range of glucose concentrations.
| Original language | English |
|---|---|
| Pages (from-to) | 7-13 |
| Number of pages | 7 |
| Journal | Sensors and Actuators, A: Physical |
| Volume | 128 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2006 Mar 31 |
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Keywords
- Carbon nanotube
- Glucose-detection
- Microfluidics
- PDMS
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Mechanical Engineering
- Instrumentation
Cite this
Integration of enzyme immobilized single-walled carbon nanotubes mass into the microfluidic platform and its application for the glucose-detection. / Kim, Jeongyun; Baek, Juyeoul; Kim, Hyughan; Lee, Kyam; Lee, Sang Hoon.
In: Sensors and Actuators, A: Physical, Vol. 128, No. 1, 31.03.2006, p. 7-13.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Integration of enzyme immobilized single-walled carbon nanotubes mass into the microfluidic platform and its application for the glucose-detection
AU - Kim, Jeongyun
AU - Baek, Juyeoul
AU - Kim, Hyughan
AU - Lee, Kyam
AU - Lee, Sang Hoon
PY - 2006/3/31
Y1 - 2006/3/31
N2 - We propose in this paper a new, simple, and cost-effective approach to two tasks: first, the fabrication of a co-enzyme-immobilized mass of single-walled carbon nanotubes (SWNTs) that has a specific microscale shape; second, the integration of the mass into a poly(dimethylsiloxane) (PDMS)-based microfluidic channel. An 80-μm-thick horseshoe-shaped SWNT microblock that had been physically immobilized with glucose oxidase (GOx) and horseradish peroxidase (HRP) was fabricated through the use of a 150-μm-thick flexible PDMS mold. The fabricated SWNT microblock was incorporated into the microfluidic channel for the bio-reaction on a microscale. This microfluidic device was tested for the spectroscopic glucose-detection, and the results showed that the glucose can be detected linearly (in log scale) in a wide range of glucose concentrations.
AB - We propose in this paper a new, simple, and cost-effective approach to two tasks: first, the fabrication of a co-enzyme-immobilized mass of single-walled carbon nanotubes (SWNTs) that has a specific microscale shape; second, the integration of the mass into a poly(dimethylsiloxane) (PDMS)-based microfluidic channel. An 80-μm-thick horseshoe-shaped SWNT microblock that had been physically immobilized with glucose oxidase (GOx) and horseradish peroxidase (HRP) was fabricated through the use of a 150-μm-thick flexible PDMS mold. The fabricated SWNT microblock was incorporated into the microfluidic channel for the bio-reaction on a microscale. This microfluidic device was tested for the spectroscopic glucose-detection, and the results showed that the glucose can be detected linearly (in log scale) in a wide range of glucose concentrations.
KW - Carbon nanotube
KW - Glucose-detection
KW - Microfluidics
KW - PDMS
UR - http://www.scopus.com/inward/record.url?scp=33645163291&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645163291&partnerID=8YFLogxK
U2 - 10.1016/j.sna.2005.12.039
DO - 10.1016/j.sna.2005.12.039
M3 - Article
VL - 128
SP - 7
EP - 13
JO - Sensors and Actuators, A: Physical
JF - Sensors and Actuators, A: Physical
SN - 0924-4247
IS - 1
ER -