@inbook{2562c078183646bca781ffece334f1ca,
title = "Interrogating Fiber Formation Kinetics with Automated 2D-IR Spectroscopy",
abstract = "A new method for collecting 2D-IR spectra that utilizes both a pump-probe beam geometry and a mid-IR pulse shaper is used to gain a fuller understanding of fiber formation in the human islet amyloid polypeptide (hIAPP). We extract structural kinetics in order to better understand aggregation in hIAPP, the protein component of the amyloid fibers found to inhibit insulin production in type II diabetes patients.",
keywords = "Amyloid Fiber, Amyloid Formation, Cross Peak, Fiber Formation, Random Coil",
author = "Strasfeld, {David B.} and Ling, {Yun L.} and Shim, {Sang Hee} and Zanni, {Martin T.}",
note = "Funding Information: We acknowledge the contributions of Dan Raleigh and Peter Marek from SUNY ? Stony Brook for synthesizing the isotope labeled hIAPP. Funding comes from the NSF (CHE-0350518), the Packard Foundation, and the NIH (R21AI064797, R01DK079895). Publisher Copyright: {\textcopyright} 2009, Springer-Verlag Berlin Heidelberg.",
year = "2009",
doi = "10.1007/978-3-540-95946-5_177",
language = "English",
series = "Springer Series in Chemical Physics",
publisher = "Springer Science and Business Media Deutschland GmbH",
pages = "547--549",
booktitle = "Springer Series in Chemical Physics",
address = "Germany",
}
