Intracranial stenting as a rescue therapy in patients with stroke-in-evolution

Woo Keun Seo, Kyungmi Oh, Sang Il Suh, Hae Young Seol

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)

    Abstract

    Background The feasibility and efficacy of intracranial stenting were evaluated for patients with a stroke-in-evolution after the time window for thrombolysis. Methods Patients with symptomatic intracranial steno-occlusive disease with progressive or fluctuating symptoms were treated using intracranial stenting after the time window for hyperacute thrombolysis. Results Within the study period, we identified 10 patients (7 men, 62.5 ± 11.3 years old) who were eligible for inclusion. The median onset-to-arrival time was 5.8 hours (range:.6-144 hours), and the median onset-to-procedure time was 33 hours (range: 8-346 hours). Only 1 patient previously received intravenous thrombolysis using alteplase. The symptomatic occlusive artery was the right middle cerebral artery, left middle cerebral artery, and basilar artery in 3, 1, and 6 patients, respectively. The median initial National Institutes of Health Stroke Scale (NIHSS) score was 4 (range: 0-6), and the median NIHSS score measured immediately before the procedure was 8 (range: 4-26). All but 1 patient underwent successful angioplasty and stenting using a Wingspan stent. Reocclusion of the stented artery occurred in 1 patient, and his neurological status deteriorated to coma. A favorable outcome (modified Rankin Scale ≤2) at 3 months was noted in 7 patients (70%). Conclusion Intracranial stenting could be considered an alternative strategy for treating patients with medically intractable stroke-in-evolution.

    Original languageEnglish
    Pages (from-to)1411-1416
    Number of pages6
    JournalJournal of Stroke and Cerebrovascular Diseases
    Volume25
    Issue number6
    DOIs
    Publication statusPublished - 2016 Jun 1

    Keywords

    • Brain infarct
    • neurological deterioration
    • outcome
    • stents

    ASJC Scopus subject areas

    • Surgery
    • Rehabilitation
    • Clinical Neurology
    • Cardiology and Cardiovascular Medicine

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