Intravaginal packing effects of CT-guided intracavitary radiotherapy for cervical cancer

Doo Hyun Lee, Jung Keun Cho, Kyung Hwan Shin, Dongho Shin, Myonggeun Yoon, Sung Yong Park, Se Byeong Lee, Joo Young Kim, Kwan Ho Cho, Tae Suk Suh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ten plans for Ir 192 high-dose-rate ICR after 30-40 Gy external beam radiotherapy were investigated. The ICR prescription dose for an each insertion was 4 or 5 Gy to point A, twice weekly, and the total dose of ICR ranged from 24 to 30 Gy (median, 24). A fractional 100% dose was prescribed to point A. Two sets of CT images before and after packing were acquired at the first ICR session with artifactfree applicators in place. The International Commission on Radiation Units and Measurements Report 38 (ICRU-38) rectal and bladder points, and the percentage of volumes receiving 50%, 80%, and 100% of the prescribed dose were also analyzed and compared. Conventional point A plans were performed. The mean values of the bladder and rectal ICRU- 38 point doses before packing, 109.93% and 117.80%, were decreased after packing to 98.85% and 94.93%, respectively, with the difference being marginally significant (p=0.013) (Edthis p value is not significant at all). The maximum point doses of the bladder and rectum were decreased by 20.12% and 16.01%, respectively. The mean-volume fractions of the bladder receiving 50%, 80%, and 100% of the reference dose were decreased by 8.29%, 4.48% and 2.64%, while the decrease of the mean-volume fractions for the rectum were relatively small at 4.44%, 1.52% and 1.20%, respectively. However, this reduction was not significant based on a p value of about 0.15~0.81. While the dose at the reference point was decreased significantly due to the packing effects, the presence or absence of packing had little effect on volumetric doses because the volumes enlarged by the packing effects were relatively small compared to the volume of the entire bladder and rectum itself. The packing is still needed as it could reduce the complications caused by the high point dose and decrease the maximum dose.

Original languageEnglish
Title of host publicationIFMBE Proceedings
PublisherSpringer Verlag
Pages1742-1745
Number of pages4
Volume14
Edition1
Publication statusPublished - 2007
Externally publishedYes
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: 2006 Aug 272006 Sep 1

Other

Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
CountryKorea, Republic of
CitySeoul
Period06/8/2706/9/1

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Radiotherapy
Volume fraction
Applicators
Dosimetry
Radiation

Keywords

  • Intracavitary radiotherapy
  • Intravaginal packing

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

Cite this

Lee, D. H., Cho, J. K., Shin, K. H., Shin, D., Yoon, M., Park, S. Y., ... Suh, T. S. (2007). Intravaginal packing effects of CT-guided intracavitary radiotherapy for cervical cancer. In IFMBE Proceedings (1 ed., Vol. 14, pp. 1742-1745). Springer Verlag.

Intravaginal packing effects of CT-guided intracavitary radiotherapy for cervical cancer. / Lee, Doo Hyun; Cho, Jung Keun; Shin, Kyung Hwan; Shin, Dongho; Yoon, Myonggeun; Park, Sung Yong; Lee, Se Byeong; Kim, Joo Young; Cho, Kwan Ho; Suh, Tae Suk.

IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. p. 1742-1745.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lee, DH, Cho, JK, Shin, KH, Shin, D, Yoon, M, Park, SY, Lee, SB, Kim, JY, Cho, KH & Suh, TS 2007, Intravaginal packing effects of CT-guided intracavitary radiotherapy for cervical cancer. in IFMBE Proceedings. 1 edn, vol. 14, Springer Verlag, pp. 1742-1745, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 06/8/27.
Lee DH, Cho JK, Shin KH, Shin D, Yoon M, Park SY et al. Intravaginal packing effects of CT-guided intracavitary radiotherapy for cervical cancer. In IFMBE Proceedings. 1 ed. Vol. 14. Springer Verlag. 2007. p. 1742-1745
Lee, Doo Hyun ; Cho, Jung Keun ; Shin, Kyung Hwan ; Shin, Dongho ; Yoon, Myonggeun ; Park, Sung Yong ; Lee, Se Byeong ; Kim, Joo Young ; Cho, Kwan Ho ; Suh, Tae Suk. / Intravaginal packing effects of CT-guided intracavitary radiotherapy for cervical cancer. IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. pp. 1742-1745
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abstract = "Ten plans for Ir 192 high-dose-rate ICR after 30-40 Gy external beam radiotherapy were investigated. The ICR prescription dose for an each insertion was 4 or 5 Gy to point A, twice weekly, and the total dose of ICR ranged from 24 to 30 Gy (median, 24). A fractional 100{\%} dose was prescribed to point A. Two sets of CT images before and after packing were acquired at the first ICR session with artifactfree applicators in place. The International Commission on Radiation Units and Measurements Report 38 (ICRU-38) rectal and bladder points, and the percentage of volumes receiving 50{\%}, 80{\%}, and 100{\%} of the prescribed dose were also analyzed and compared. Conventional point A plans were performed. The mean values of the bladder and rectal ICRU- 38 point doses before packing, 109.93{\%} and 117.80{\%}, were decreased after packing to 98.85{\%} and 94.93{\%}, respectively, with the difference being marginally significant (p=0.013) (Edthis p value is not significant at all). The maximum point doses of the bladder and rectum were decreased by 20.12{\%} and 16.01{\%}, respectively. The mean-volume fractions of the bladder receiving 50{\%}, 80{\%}, and 100{\%} of the reference dose were decreased by 8.29{\%}, 4.48{\%} and 2.64{\%}, while the decrease of the mean-volume fractions for the rectum were relatively small at 4.44{\%}, 1.52{\%} and 1.20{\%}, respectively. However, this reduction was not significant based on a p value of about 0.15~0.81. While the dose at the reference point was decreased significantly due to the packing effects, the presence or absence of packing had little effect on volumetric doses because the volumes enlarged by the packing effects were relatively small compared to the volume of the entire bladder and rectum itself. The packing is still needed as it could reduce the complications caused by the high point dose and decrease the maximum dose.",
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AB - Ten plans for Ir 192 high-dose-rate ICR after 30-40 Gy external beam radiotherapy were investigated. The ICR prescription dose for an each insertion was 4 or 5 Gy to point A, twice weekly, and the total dose of ICR ranged from 24 to 30 Gy (median, 24). A fractional 100% dose was prescribed to point A. Two sets of CT images before and after packing were acquired at the first ICR session with artifactfree applicators in place. The International Commission on Radiation Units and Measurements Report 38 (ICRU-38) rectal and bladder points, and the percentage of volumes receiving 50%, 80%, and 100% of the prescribed dose were also analyzed and compared. Conventional point A plans were performed. The mean values of the bladder and rectal ICRU- 38 point doses before packing, 109.93% and 117.80%, were decreased after packing to 98.85% and 94.93%, respectively, with the difference being marginally significant (p=0.013) (Edthis p value is not significant at all). The maximum point doses of the bladder and rectum were decreased by 20.12% and 16.01%, respectively. The mean-volume fractions of the bladder receiving 50%, 80%, and 100% of the reference dose were decreased by 8.29%, 4.48% and 2.64%, while the decrease of the mean-volume fractions for the rectum were relatively small at 4.44%, 1.52% and 1.20%, respectively. However, this reduction was not significant based on a p value of about 0.15~0.81. While the dose at the reference point was decreased significantly due to the packing effects, the presence or absence of packing had little effect on volumetric doses because the volumes enlarged by the packing effects were relatively small compared to the volume of the entire bladder and rectum itself. The packing is still needed as it could reduce the complications caused by the high point dose and decrease the maximum dose.

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