Intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema.

Young Jae Choi, In Kyung Oh, Jae Ryung Oh, Kuhl Huh

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

PURPOSE: To compare the short-term effects of intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema. METHODS: This is a prospective and interventional study. Sixty eyes of 60 patients who had diffuse diabetic macular edema were assigned to receive a single intravitreal injection (4 mg) or a single posterior subtenon injection (40 mg) of triamcinolone acetonide. The central retinal thickness was measured using optical coherent tomography before injection and at 1 and 3 months after injection. Visual acuity and intraocular pressure (IOP) were also measured. RESULTS: Both intravitreal and posterior subtenon injections of triamcinolone acetonide resulted in significant improvements in visual acuity at 1 month and 3 months after injection. Both groups resulted in a significant decrease in central macular thickness (CMT) at 1 month and 3 months post-injection. IOP in the intravitreal injection group was significantly higher than in the posterior subtenon injection group at 3 months after injection. CONCLUSIONS: The posterior subtenon injection of triamcinolone acetonide had a comparable effect to the intravitreal triamcinolone injection and showed a lower risk of elevated IOP. Posterior subtenon injection of triamcinolone acetonide may be a good alternative for the treatment of diffuse diabetic macular edema.

Original languageEnglish
Pages (from-to)205-209
Number of pages5
JournalKorean journal of ophthalmology : KJO
Volume20
Issue number4
Publication statusPublished - 2006 Dec 1

Fingerprint

Triamcinolone Acetonide
Macular Edema
Injections
Intravitreal Injections
Intraocular Pressure
Visual Acuity
Optical Tomography
Triamcinolone
Prospective Studies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema. / Choi, Young Jae; Oh, In Kyung; Oh, Jae Ryung; Huh, Kuhl.

In: Korean journal of ophthalmology : KJO, Vol. 20, No. 4, 01.12.2006, p. 205-209.

Research output: Contribution to journalArticle

@article{540be0ccb9644282b10c00d4c30fbd39,
title = "Intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema.",
abstract = "PURPOSE: To compare the short-term effects of intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema. METHODS: This is a prospective and interventional study. Sixty eyes of 60 patients who had diffuse diabetic macular edema were assigned to receive a single intravitreal injection (4 mg) or a single posterior subtenon injection (40 mg) of triamcinolone acetonide. The central retinal thickness was measured using optical coherent tomography before injection and at 1 and 3 months after injection. Visual acuity and intraocular pressure (IOP) were also measured. RESULTS: Both intravitreal and posterior subtenon injections of triamcinolone acetonide resulted in significant improvements in visual acuity at 1 month and 3 months after injection. Both groups resulted in a significant decrease in central macular thickness (CMT) at 1 month and 3 months post-injection. IOP in the intravitreal injection group was significantly higher than in the posterior subtenon injection group at 3 months after injection. CONCLUSIONS: The posterior subtenon injection of triamcinolone acetonide had a comparable effect to the intravitreal triamcinolone injection and showed a lower risk of elevated IOP. Posterior subtenon injection of triamcinolone acetonide may be a good alternative for the treatment of diffuse diabetic macular edema.",
author = "Choi, {Young Jae} and Oh, {In Kyung} and Oh, {Jae Ryung} and Kuhl Huh",
year = "2006",
month = "12",
day = "1",
language = "English",
volume = "20",
pages = "205--209",
journal = "Korean journal of ophthalmology : KJO",
issn = "1011-8942",
publisher = "Seoul Kjo",
number = "4",

}

TY - JOUR

T1 - Intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema.

AU - Choi, Young Jae

AU - Oh, In Kyung

AU - Oh, Jae Ryung

AU - Huh, Kuhl

PY - 2006/12/1

Y1 - 2006/12/1

N2 - PURPOSE: To compare the short-term effects of intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema. METHODS: This is a prospective and interventional study. Sixty eyes of 60 patients who had diffuse diabetic macular edema were assigned to receive a single intravitreal injection (4 mg) or a single posterior subtenon injection (40 mg) of triamcinolone acetonide. The central retinal thickness was measured using optical coherent tomography before injection and at 1 and 3 months after injection. Visual acuity and intraocular pressure (IOP) were also measured. RESULTS: Both intravitreal and posterior subtenon injections of triamcinolone acetonide resulted in significant improvements in visual acuity at 1 month and 3 months after injection. Both groups resulted in a significant decrease in central macular thickness (CMT) at 1 month and 3 months post-injection. IOP in the intravitreal injection group was significantly higher than in the posterior subtenon injection group at 3 months after injection. CONCLUSIONS: The posterior subtenon injection of triamcinolone acetonide had a comparable effect to the intravitreal triamcinolone injection and showed a lower risk of elevated IOP. Posterior subtenon injection of triamcinolone acetonide may be a good alternative for the treatment of diffuse diabetic macular edema.

AB - PURPOSE: To compare the short-term effects of intravitreal versus posterior subtenon injection of triamcinolone acetonide for diabetic macular edema. METHODS: This is a prospective and interventional study. Sixty eyes of 60 patients who had diffuse diabetic macular edema were assigned to receive a single intravitreal injection (4 mg) or a single posterior subtenon injection (40 mg) of triamcinolone acetonide. The central retinal thickness was measured using optical coherent tomography before injection and at 1 and 3 months after injection. Visual acuity and intraocular pressure (IOP) were also measured. RESULTS: Both intravitreal and posterior subtenon injections of triamcinolone acetonide resulted in significant improvements in visual acuity at 1 month and 3 months after injection. Both groups resulted in a significant decrease in central macular thickness (CMT) at 1 month and 3 months post-injection. IOP in the intravitreal injection group was significantly higher than in the posterior subtenon injection group at 3 months after injection. CONCLUSIONS: The posterior subtenon injection of triamcinolone acetonide had a comparable effect to the intravitreal triamcinolone injection and showed a lower risk of elevated IOP. Posterior subtenon injection of triamcinolone acetonide may be a good alternative for the treatment of diffuse diabetic macular edema.

UR - http://www.scopus.com/inward/record.url?scp=33847710254&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33847710254&partnerID=8YFLogxK

M3 - Article

VL - 20

SP - 205

EP - 209

JO - Korean journal of ophthalmology : KJO

JF - Korean journal of ophthalmology : KJO

SN - 1011-8942

IS - 4

ER -