Is median nerve enlargement at the wrist associated with tremor in Parkinson disease?

Seung Nam Yang, Hyo Jeong Kang, Joon Shik Yoon, Sun Jae Won, Woo Keun Seo, Seong Beom Koh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives - Tremor is one of the cardinal features of Parkinson disease (PD) and may cause cumulative trauma-related injury to nerves of the hands. The aim of this study was to assess the electrodiagnostic and sonographic features of patients with PD and to assess the effect of tremor in PD on the median nerve. Methods - We studied 31 hands of healthy control participants (n = 16; mean age ± SD, 60.25 ± 14.67 years) and 81 hands of patients with PD (n = 42; 64.95 ± 11.13 years). Motor symptoms were measured by the Unified Parkinson's Disease Rating Scale III. Median nerve conduction studies and sonographic cross-sectional area measurements were performed in all participants. Results - The median nerve cross-sectional area in patients with PD (10.71 ± 2.79 mm2) was significantly larger than that in the control group (7.40 ± 1.05 mm2; P < .05). However, there was no significant difference in median nerve electrodiagnostic findings between the PD and control groups. The median nerve cross-sectional area was associated with the severity of the tremor but not with the Unified Parkinson's Disease Rating Scale motor score. Conclusions - Tremor in PD is associated with median nerve enlargement but not with impairment of median nerve conduction.

Original languageEnglish
Pages (from-to)2079-2083
Number of pages5
JournalJournal of Ultrasound in Medicine
Volume33
Issue number12
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Median Nerve
Tremor
Wrist
Parkinson Disease
Hand
Neural Conduction
Control Groups
Wounds and Injuries
Healthy Volunteers
Cross-Sectional Studies

Keywords

  • Median nerve
  • Musculoskeletal ultrasound
  • Parkinson disease
  • Sonography
  • Tremor

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Is median nerve enlargement at the wrist associated with tremor in Parkinson disease? / Yang, Seung Nam; Kang, Hyo Jeong; Yoon, Joon Shik; Won, Sun Jae; Seo, Woo Keun; Koh, Seong Beom.

In: Journal of Ultrasound in Medicine, Vol. 33, No. 12, 01.01.2014, p. 2079-2083.

Research output: Contribution to journalArticle

@article{911f3e6a663549de839de8f1707ad891,
title = "Is median nerve enlargement at the wrist associated with tremor in Parkinson disease?",
abstract = "Objectives - Tremor is one of the cardinal features of Parkinson disease (PD) and may cause cumulative trauma-related injury to nerves of the hands. The aim of this study was to assess the electrodiagnostic and sonographic features of patients with PD and to assess the effect of tremor in PD on the median nerve. Methods - We studied 31 hands of healthy control participants (n = 16; mean age ± SD, 60.25 ± 14.67 years) and 81 hands of patients with PD (n = 42; 64.95 ± 11.13 years). Motor symptoms were measured by the Unified Parkinson's Disease Rating Scale III. Median nerve conduction studies and sonographic cross-sectional area measurements were performed in all participants. Results - The median nerve cross-sectional area in patients with PD (10.71 ± 2.79 mm2) was significantly larger than that in the control group (7.40 ± 1.05 mm2; P < .05). However, there was no significant difference in median nerve electrodiagnostic findings between the PD and control groups. The median nerve cross-sectional area was associated with the severity of the tremor but not with the Unified Parkinson's Disease Rating Scale motor score. Conclusions - Tremor in PD is associated with median nerve enlargement but not with impairment of median nerve conduction.",
keywords = "Median nerve, Musculoskeletal ultrasound, Parkinson disease, Sonography, Tremor",
author = "Yang, {Seung Nam} and Kang, {Hyo Jeong} and Yoon, {Joon Shik} and Won, {Sun Jae} and Seo, {Woo Keun} and Koh, {Seong Beom}",
year = "2014",
month = "1",
day = "1",
doi = "10.7863/ultra.33.12.2079",
language = "English",
volume = "33",
pages = "2079--2083",
journal = "Journal of Ultrasound in Medicine",
issn = "0278-4297",
publisher = "American Institute of Ultrasound in Medicine",
number = "12",

}

TY - JOUR

T1 - Is median nerve enlargement at the wrist associated with tremor in Parkinson disease?

AU - Yang, Seung Nam

AU - Kang, Hyo Jeong

AU - Yoon, Joon Shik

AU - Won, Sun Jae

AU - Seo, Woo Keun

AU - Koh, Seong Beom

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Objectives - Tremor is one of the cardinal features of Parkinson disease (PD) and may cause cumulative trauma-related injury to nerves of the hands. The aim of this study was to assess the electrodiagnostic and sonographic features of patients with PD and to assess the effect of tremor in PD on the median nerve. Methods - We studied 31 hands of healthy control participants (n = 16; mean age ± SD, 60.25 ± 14.67 years) and 81 hands of patients with PD (n = 42; 64.95 ± 11.13 years). Motor symptoms were measured by the Unified Parkinson's Disease Rating Scale III. Median nerve conduction studies and sonographic cross-sectional area measurements were performed in all participants. Results - The median nerve cross-sectional area in patients with PD (10.71 ± 2.79 mm2) was significantly larger than that in the control group (7.40 ± 1.05 mm2; P < .05). However, there was no significant difference in median nerve electrodiagnostic findings between the PD and control groups. The median nerve cross-sectional area was associated with the severity of the tremor but not with the Unified Parkinson's Disease Rating Scale motor score. Conclusions - Tremor in PD is associated with median nerve enlargement but not with impairment of median nerve conduction.

AB - Objectives - Tremor is one of the cardinal features of Parkinson disease (PD) and may cause cumulative trauma-related injury to nerves of the hands. The aim of this study was to assess the electrodiagnostic and sonographic features of patients with PD and to assess the effect of tremor in PD on the median nerve. Methods - We studied 31 hands of healthy control participants (n = 16; mean age ± SD, 60.25 ± 14.67 years) and 81 hands of patients with PD (n = 42; 64.95 ± 11.13 years). Motor symptoms were measured by the Unified Parkinson's Disease Rating Scale III. Median nerve conduction studies and sonographic cross-sectional area measurements were performed in all participants. Results - The median nerve cross-sectional area in patients with PD (10.71 ± 2.79 mm2) was significantly larger than that in the control group (7.40 ± 1.05 mm2; P < .05). However, there was no significant difference in median nerve electrodiagnostic findings between the PD and control groups. The median nerve cross-sectional area was associated with the severity of the tremor but not with the Unified Parkinson's Disease Rating Scale motor score. Conclusions - Tremor in PD is associated with median nerve enlargement but not with impairment of median nerve conduction.

KW - Median nerve

KW - Musculoskeletal ultrasound

KW - Parkinson disease

KW - Sonography

KW - Tremor

UR - http://www.scopus.com/inward/record.url?scp=84919342726&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84919342726&partnerID=8YFLogxK

U2 - 10.7863/ultra.33.12.2079

DO - 10.7863/ultra.33.12.2079

M3 - Article

VL - 33

SP - 2079

EP - 2083

JO - Journal of Ultrasound in Medicine

JF - Journal of Ultrasound in Medicine

SN - 0278-4297

IS - 12

ER -