TY - JOUR
T1 - Isolated labyrinthine infarction as a harbinger of anterior inferior cerebellar artery territory infarction with normal diffusion-weighted brain MRI
AU - Kim, Ji Soo
AU - Cho, Kyung Hee
AU - Lee, Hyung
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009/3/15
Y1 - 2009/3/15
N2 - Objectives: This paper aims to determine the frequency of isolated labyrinthine infarction as an initial manifestation of anterior inferior cerebellar artery (AICA) territory infarction and discuss its clinical implication. Methods: We studied 54 consecutive patients with AICA infarction diagnosed by brain MRI from the acute stroke registry. Results: We identified 4 patients (7.4%) with AICA territory infarction who initially presented with vertigo and hearing loss mimicking acute labyrinthitis and subsequently suffered from delayed neurological deficits. All patients had normal brain MRIs including diffusion-weighted images at the time of isolated audiovestibular loss, but all subsequently exhibited acute infarct(s) in the AICA territory on follow-up brain MRIs when they developed additional neurological deficits. Conclusion: Labyrinthine infarction may be a warning sign of impending pontocerebellar infarction in the AICA territory. Our results indicate that even a classical peripheral presentation, e.g., acute hearing loss, and acute vertigo with unidirectional nystagmus, may be a manifestation of ischemic stroke in the posterior circulation.
AB - Objectives: This paper aims to determine the frequency of isolated labyrinthine infarction as an initial manifestation of anterior inferior cerebellar artery (AICA) territory infarction and discuss its clinical implication. Methods: We studied 54 consecutive patients with AICA infarction diagnosed by brain MRI from the acute stroke registry. Results: We identified 4 patients (7.4%) with AICA territory infarction who initially presented with vertigo and hearing loss mimicking acute labyrinthitis and subsequently suffered from delayed neurological deficits. All patients had normal brain MRIs including diffusion-weighted images at the time of isolated audiovestibular loss, but all subsequently exhibited acute infarct(s) in the AICA territory on follow-up brain MRIs when they developed additional neurological deficits. Conclusion: Labyrinthine infarction may be a warning sign of impending pontocerebellar infarction in the AICA territory. Our results indicate that even a classical peripheral presentation, e.g., acute hearing loss, and acute vertigo with unidirectional nystagmus, may be a manifestation of ischemic stroke in the posterior circulation.
KW - Anterior inferior cerebellar artery
KW - Infarction
KW - Inner ear
KW - Prodrome
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U2 - 10.1016/j.jns.2008.12.002
DO - 10.1016/j.jns.2008.12.002
M3 - Article
C2 - 19135217
AN - SCOPUS:58749087870
VL - 278
SP - 82
EP - 84
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
SN - 0022-510X
IS - 1-2
ER -